Thiamine Impurity N1 CAS 7403-34-1

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.7403-34-1
Molecular FormulaC7H8N4S
Molecular Weight180.23 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Thiamine Impurity N1 CAS 7403-34-1 chemical structure

Description

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

Thiamine Impurity N1 (CAS 7403-34-1) is a certified pharmaceutical impurity reference standard with the molecular formula C7H8N4S and a molecular weight of 180.23 g/mol.

The molecular framework of Thiamine Impurity N1 (C7H8N4S) is characterized by a nitrile group, sulfur-containing functionality, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

As a certified reference material (CRM), Thiamine Impurity N1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC7H8N4S
Molecular Weight180.23 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1959
Nitrogen Atoms4
Sulfur Atoms1

Related Thiamine Standards

Recommended Standards

Why CATO?