Bis(methylthio)gliotoxin (FR-49175) CAS 74149-38-5
| CAS No. | 74149-38-5 |
| Molecular Formula | C15H20N2O4S2 |
| Molecular Weight | 356.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Bis(methylthio)gliotoxin (FR-49175) (C15H20N2O4S2) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Bis(methylthio)gliotoxin (FR-49175) (CAS 74149-38-5), a certified reference material (molecular formula C15H20N2O4S2, MW 356.46 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Bis(methylthio)gliotoxin (FR-49175) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H20N2O4S2 |
| Molecular Weight | 356.46 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Bis Standards
- 2,6-Bis(methylthio)-3,5-diphenyl-4H-thiopyran-4-one (CAS 24097-29-8)
- 4-(4-Methyl-5-(methylthio)-4H-1,2,4-triazol-3-yl)-2-(3-(trifluoromethyl)phenyl)thiazole (CAS 400083-71-8)
- (6-Methyl-3-(methylthio)-5-oxo-1,2,4-triazin-4(5H)-yl)methyl 2-(4-chlorophenoxy)acetate (CAS 877648-41-4)
- (6-Methyl-3-(methylthio)-5-oxo-1,2,4-triazin-4(5H)-yl)methyl 5-chloro-2-methoxybenzoate (CAS 877643-01-1)
- Ethyl 2-(methylthio)-4-((3-(trifluoromethyl)phenyl)amino)pyrimidine-5-carboxylate (CAS 3859-55-0)
- Ethyl 2-(methylthio)-4-((4-(trifluoromethyl)phenyl)amino)pyrimidine-5-carboxylate (CAS 339019-43-1)
- N-(2-(Methylthio)benzo[d]thiazol-6-yl)benzo[d]thiazole-6-carboxamide (CAS 681167-06-6)
- N-(6-(Methylthio)benzo[d]thiazol-2-yl)benzo[d]thiazole-2-carboxamide (CAS 899982-80-0)
Recommended Standards
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- Crocetin dimethyl ester (CAS 5892-54-6)
- 5-Isopropyl-N-phenethyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine (CAS 890628-94-1)
- Ethyl 2-(4-((1r,3r)-3-((tert-butoxycarbonyl)amino)cyclobutoxy)piperidin-1-yl)acetate (CAS 2086301-45-1)
- (S)-1-(3-(Isopropylamino)piperidin-1-yl)ethanone (CAS 1354018-14-6)
- (2S,6S)-2,6-Diethyl-4-oxo-piperidine-1-carboxylic acid tert-butyl ester (CAS 2165801-58-9)
- Dimethyl 1-(2-(3-(2-fluorophenyl)ureido)-2-oxoethyl)-1H-1,2,3-triazole-4,5-dicarboxylate (CAS 892278-15-8)
- 2-Methoxycyclohexanol (CAS 2979-24-0)
- 3-Bromo-6-methoxy-2H-chromen-2-one (CAS 1026715-03-6)
- 2-(6-(Cyclopropylamino)pyridin-3-yl)piperidine-1-carbaldehyde (CAS 1352511-05-7)
- 2-(Pyrazin-2-yl)-N-(4-(trifluoromethoxy)phenyl)thiazole-4-carboxamide (CAS 1234808-01-5)
- 4-Methyl-2-(1-phenylethyl)-1,3-dioxolane (CAS 67634-23-5)
- Bis(3-hydroxy-2,3-dimethylbutan-2-yl) (2-((4-fluorobenzyl)amino)phenyl)boronate (CAS 1259285-58-9)
- Semaglutide impurity 109 (CAS CATO-C4X-2226109)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com