5-Fluoro-2-naphthalenol CAS 741693-88-9
| CAS No. | 741693-88-9 |
| Molecular Formula | C10H7FO |
| Molecular Weight | 162.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Fluoro-2-naphthalenol (CAS 741693-88-9), molecular formula C10H7FO and molecular weight 162.16 g/mol, is a CATO reference standard with documented purity and traceability.
5-Fluoro-2-naphthalenol (C10H7FO) contains a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H7FO |
| Molecular Weight | 162.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F-containing |
Related Fluoro Standards
- 4-Fluoro-1-phenyl-1H-pyrazole (CAS 1049010-89-0)
- 8-Fluoro-2-methylquinazoline (CAS 1208312-41-7)
- 6-Fluoro-2-naphthol (CAS 13101-83-2)
- 5-Fluoro-2-(1H-pyrrol-1-yl)pyridine (CAS 1355334-56-3)
- 4-Fluoro-2-(1H-pyrrol-1-yl)pyridine (CAS 1355334-73-4)
- ethyl 5-fluoro-1H-pyrazole-3-carboxylate (CAS 1416371-96-4)
- 4-Fluoro-1-hydroxycyclohexane-1-carboxylic acid (CAS 1426230-83-2)
- 2-Fluoro-2-(1-hydroxycyclopentyl)acetic acid (CAS 1512046-62-6)
Recommended Standards
- 5-Fluoro-2-methylquinazoline (CAS 583031-10-1)
- 5-Fluoronaphthalen-1-ol (CAS 61761-32-8)
- 5-(2-Fluorophenyl)-1H-imidazole (CAS 912763-52-1)
- 6-Fluoro-2-methylquinoxaline (CAS 96600-56-5)
- (6-nitroimidazo[1,2-a]pyridin-8-yl)(phenyl)methanone (CAS 929972-27-0)
- 3-Bromo-5-(pyrrolidin-1-ylsulfonyl)pyridine (CAS 1086064-89-2)
- L-Menthylmethacrylate (CAS 2231-91-6)
- 5-Iodo-2-trifluoromethoxyphenylboronic acid (CAS 1256355-12-0)
- tert-Butyl (S)-2-((2-(4-bromophenyl)-2-oxoethyl)carbamoyl)pyrrolidine-1-carboxylate (CAS 1007881-98-2)
- Cobalt(2+), tris[4-(1,1-dimethylethyl)-2-(1H-pyrazol-1-yl-κN2)pyridine-κN]-, salt with 1,1,1-trifluoro-N-[(trifluoromethyl)sulfonyl]methanesulfonamide (1:2) (CAS 1447938-65-9)
- 2-(4-Chlorophenyl)-2-(piperazin-1-yl)ethan-1-ol (CAS 1183300-99-3)
- Depreotide (CAS 161982-62-3)
- 6-Chloro-2-(4-isopropoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160263-39-7)
- (Ser(PO?H?)3??·???)-Tau Peptide (379-408) trifluoroacetate salt (CAS 2022956-60-9)
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