5-Iodo-2-trifluoromethoxyphenylboronic acid CAS 1256355-12-0
| CAS No. | 1256355-12-0 |
| Molecular Formula | C7H5BF3IO3 |
| Molecular Weight | 331.82 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
5-Iodo-2-trifluoromethoxyphenylboronic acid (CAS 1256355-12-0), molecular formula C7H5BF3IO3 and molecular weight 331.82 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Iodo-2-trifluoromethoxyphenylboronic acid (C7H5BF3IO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 5-Iodo-2-trifluoromethoxyphenylboronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H5BF3IO3 |
| Molecular Weight | 331.82 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/I-containing |
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