4-Propyl-1-sulfanyl-4h,5h-[1,2,4]triazolo[4,3-a]quinazolin-5-one CAS 741731-79-3
| CAS No. | 741731-79-3 |
| Molecular Formula | C12H12N4OS |
| Molecular Weight | 260.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Propyl-1-sulfanyl-4h,5h-[1,2,4]triazolo[4,3-a]quinazolin-5-one is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4-Propyl-1-sulfanyl-4h,5h-[1,2,4]triazolo[4,3-a]quinazolin-5-one (CAS 741731-79-3), a certified reference material (molecular formula C12H12N4OS, MW 260.31 g/mol) for analytical method development and quality control.
The molecular framework of 4-Propyl-1-sulfanyl-4h,5h-[1,2,4]triazolo[4,3-a]quinazolin-5-one (C12H12N4OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H12N4OS |
| Molecular Weight | 260.31 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Propyl Standards
- 2-Sulfanyl-1-[2-(trifluoromethyl)phenyl]-4,5-dihydro-1h-imidazol-5-one (CAS 852389-02-7)
- 11-methyl-5-sulfanyl-8-thia-4,6-diazatricyclo[7.4.0.0²,⁷]trideca-1(9),2(7),5-trien-3-one (CAS 372180-34-2)
- 4-methyl-5-sulfanyl-8-thia-4,6-diazatricyclo[7.4.0.0²,⁷]trideca-1(9),2(7),5-trien-3-one (CAS 38201-61-5)
- 1-[(4-ethyl-5-sulfanyl-4H-1,2,4-triazol-3-yl)methyl]azepan-2-one (CAS 790270-75-6)
- ethyl 2-sulfanyl-4-(trifluoromethyl)pyrimidine-5-carboxylate (CAS 676438-98-5)
- 4-Phenyl-4-sulfanyl-2-(trifluoromethyl)butanoic acid (CAS 870703-90-5)
- 3-Ethyl-2-sulfanyl-3h,4h-benzo[g]quinazolin-4-one (CAS 852218-19-0)
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Recommended Standards
- 4-Hydroxy-7,8,9-trimethylthieno[2,3-b:4,5-b']dipyridin-2(1H)-one (CAS 939888-52-5)
- 5-(Azepan-2-yl)-3-(2-fluorophenyl)isoxazole (CAS 947015-82-9)
- 4-{(2E)-2-[1-(2-Thienyl)ethylidene]-hydrazino}benzoic acid (CAS 385406-37-1)
- 5-(Benzo[d]isoxazol-3-ylmethyl)-4-ethyl-2,4-dihydro-3H-1,2,4-triazole-3-thione (CAS 860651-47-4)
- 4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)benzenamine (CAS 102771-26-6)
- 2-(Difluoromethyl)-4-fluoro-3-iodopyridine-6-carboxylic acid (CAS 1807099-92-8)
- N-(2-Furylmethyl)-N-(2-methoxyethyl)-propane-1,3-diamine (CAS 1170289-81-2)
- 1-(4'-Methoxy-[1,1'-biphenyl]-4-yl)pentan-1-one (CAS 56116-77-9)
- 2-((5-Chloro-2-nitro-4-(trifluoromethyl)phenyl)thio)-N-mesitylacetamide (CAS 217490-34-1)
- 2-(phenoxymethyl)-1,4-dihydropyrimidin-4-one hydrochloride (CAS 1790140-56-5)
- 5-Chlorobenzothiophene-2-sulfonyl Chloride (CAS 128851-98-9)
- 4-Chloro-3-methyl-6-phenylpyridazine (CAS 1416371-83-9)
- 3-(3,5-Bis(difluoromethyl)-1h-pyrazol-1-yl)propan-1-ol (CAS 1006479-76-0)
- Palmitoyl Hexapeptide-12 (CAS 171263-26-6)
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