N-Hydroxy-3-(6-hydroxy-4-oxo-1,4-dihydropyrimidin-2-yl)-2-oxopropanamide CAS 744157-26-4
| CAS No. | 744157-26-4 |
| Molecular Formula | C7H7N3O5 |
| Molecular Weight | 213.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
N-Hydroxy-3-(6-hydroxy-4-oxo-1,4-dihydropyrimidin-2-yl)-2-oxopropanamide (CAS 744157-26-4), molecular formula C7H7N3O5 and molecular weight 213.15 g/mol, is a CATO reference standard with documented purity and traceability.
N-Hydroxy-3-(6-hydroxy-4-oxo-1,4-dihydropyrimidin-2-yl)-2-oxopropanamide (C7H7N3O5) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), N-Hydroxy-3-(6-hydroxy-4-oxo-1,4-dihydropyrimidin-2-yl)-2-oxopropanamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H7N3O5 |
| Molecular Weight | 213.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 3 |
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Recommended Standards
- N-[(2,4,6-trioxotetrahydropyrimidin-5(2H)-ylidene)methyl]glycine (CAS 446830-14-4)
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- N-(2,2,2-Trifluoroacetyl)-L-valine (CAS 349-00-8)
- tert-Butyl (2,2,2-trifluoroacetyl)carbamate (CAS 81464-59-7)
- 4-Bromo-3-methyl-5-nitrobenzamide (CAS 1807208-72-5)
- 2-(2-(Hydroxymethyl)phenyl)ethan-1-ol (CAS 6346-00-5)
- 2-O-Ethyl-L-ascorbic Acid (CAS 112894-37-8)
- 1-(tert-Butoxycarbonyl)-4-(difluoromethyl)piperidine-2-carboxylic acid (CAS 2701544-45-6)
- (3-Methylcyclohexyl)(2-methylphenyl)methanamine (CAS 1250350-11-8)
- 3-Hydroxy-2-methoxy-N-methylbenzamide (CAS 1190090-16-4)
- Ethyl 4-(tert-butyl)picolinate (CAS 177784-98-4)
- 1-(Benzo[d][1,3]dioxol-5-yl)-2-methylpropan-2-ol (CAS 23037-64-1)
- 4-methyl-1-(oxan-2-yl)pyrazole (CAS 1174132-49-0)
- Semaglutide impurity 42 (CAS CATO-C4X-222642)
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