tert-Butyl (2,2,2-trifluoroacetyl)carbamate CAS 81464-59-7

Purity 97%+In StockPharmaceutical Standards
CAS No.81464-59-7
Molecular FormulaC7H10F3NO3
Molecular Weight213.15 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

tert-Butyl (2,2,2-trifluoroacetyl)carbamate CAS 81464-59-7 chemical structure

Description

The occurrence of tert-Butyl (2,2,2-trifluoroacetyl)carbamate is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

tert-Butyl (2,2,2-trifluoroacetyl)carbamate (CAS 81464-59-7) is a high-purity analytical reference standard with the molecular formula C7H10F3NO3 and a molecular weight of 213.15 g/mol.

The molecular framework of tert-Butyl (2,2,2-trifluoroacetyl)carbamate (C7H10F3NO3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), tert-Butyl (2,2,2-trifluoroacetyl)carbamate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC7H10F3NO3
Molecular Weight213.15 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO, water
StabilityLight-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)2.0
CAS Registry Year (est.)1980
Halogen ContentF-containing
Nitrogen Atoms1

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