1-(2-(Difluoromethoxy)phenyl)piperazine CAS 744179-33-7

Purity 97%+In StockPharmaceutical Standards
CAS No.744179-33-7
Molecular FormulaC11H14F2N2O
Molecular Weight228.24 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(2-(Difluoromethoxy)phenyl)piperazine CAS 744179-33-7 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 228.24 g/mol gives 1-(2-(Difluoromethoxy)phenyl)piperazine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

1-(2-(Difluoromethoxy)phenyl)piperazine (CAS 744179-33-7) is a high-purity analytical reference standard with the molecular formula C11H14F2N2O and a molecular weight of 228.24 g/mol.

1-(2-(Difluoromethoxy)phenyl)piperazine (C11H14F2N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1-(2-(Difluoromethoxy)phenyl)piperazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H14F2N2O
Molecular Weight228.24 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1986
Halogen ContentF-containing
Nitrogen Atoms2

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