4-(Trifluoromethyl)phenylacetyl chloride CAS 74426-51-0
| CAS No. | 74426-51-0 |
| Molecular Formula | C9H6ClF3O |
| Molecular Weight | 222.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(Trifluoromethyl)phenylacetyl chloride.
4-(Trifluoromethyl)phenylacetyl chloride (CAS 74426-51-0), molecular formula C9H6ClF3O and molecular weight 222.59 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C9H6ClF3O, 4-(Trifluoromethyl)phenylacetyl chloride contains a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 222.59 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H6ClF3O |
| Molecular Weight | 222.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | F/Cl-containing |
Related Trifluoromethyl Standards
- 3-methyl-4-(trifluoromethyl)benzoyl chloride (CAS 1150464-24-6)
- 3-(Trifluoromethyl)phenylacetyl chloride (CAS 2003-14-7)
- 3-Methyl-5-(trifluoromethyl)benzoyl chloride (CAS 261952-09-4)
- 4-Methyl-2-(trifluoromethyl)benzoyl chloride (CAS 261952-10-7)
- 261952-07-2 2-Methyl-3-(trifluoromethyl)benzoyl chloride MFCD01631598 (CAS 261952-07-2)
- 261952-08-3 2-methyl-5-(trifluoromethyl)benzoyl Chloride DTXSID20379609 (CAS 261952-08-3)
- 261952-11-8 4 - Methyl - 3 - (trifluoromethyl)benzoyl chloride 4-Methyl-3-trifluoromethyl-benzoyl chloride benzoyl chloride, 4-methyl-3-(trifluoromethyl)- (CAS 261952-11-8)
- 886502-66-5 5-Methyl-2-(trifluoromethyl)benzoyl chloride MFCD06660292 (CAS 886502-66-5)
Recommended Standards
- 3-Chloro-6-cyclopropyl-4-(trifluoromethyl)pyridazine (CAS 929971-87-9)
- 6-Chloro-4-nitro-1H-indazole-3-carbonitrile (CAS 885519-37-9)
- 3-Chloro-4-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[c]pyridazine (CAS 939758-08-4)
- 3’-Chloro-5’-(trifluoromethyl)acetophenone (CAS 886497-11-6)
- N-(4-fluorophenyl)-2-(2-formylphenoxy)acetamide (CAS 428489-90-1)
- Ethyl 2-(5-methyl-3-phenyl-1H-pyrazol-1-yl)acetate (CAS 1559061-13-0)
- 5-bromo-1-tosyl-1,5,6,7-tetrahydro-4H-indol-4-one (CAS 76989-06-5)
- (S)-4-Isopropyl-4-methyloxazolidine-2,5-dione (CAS 367274-59-7)
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- 5-((2,4-Dimethylphenoxy)methyl)-1,3,4-thiadiazol-2-amine (CAS 119869-04-4)
- Methyl 2-(1-aminoethyl)thiazole-5-carboxylate (CAS 1095824-68-2)
- 4,6-Dibromo-5-(difluoromethyl)nicotinic acid (CAS 1805245-08-2)
- Latanoprostene bunod (CAS 860005-21-6)
- Tirzepatide Impurity 25 X TFA Salt (CAS CATO-C4X-324025)
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