Levonorgestrel Impurity N1 CAS 7443-72-3
| CAS No. | 7443-72-3 |
| Molecular Formula | C20H26O2 |
| Molecular Weight | 298.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Levonorgestrel Impurity N1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Levonorgestrel Impurity N1 (CAS 7443-72-3) is a certified pharmaceutical impurity reference standard with the molecular formula C20H26O2 and a molecular weight of 298.42 g/mol.
Levonorgestrel Impurity N1 (C20H26O2) contains a steroid core, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C20H26O2 |
| Molecular Weight | 298.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
Related Levonorgestrel Standards
- Levonorgestrel Impurity 4 (Ethylmetrienone) (CAS 848-04-4)
- Levonorgestrel EP Impurity D (CAS 32419-58-2)
- Levonorgestrel EP Impurity R (CAS 2322-77-2)
- Levonorgestrel EP Impurity Q (CAS 14507-49-4)
- Levonorgestrel EP Impurity W (CAS 155683-59-3)
- Levonorgestrel Impurity 33 (CAS 93798-38-0)
- Levonorgestrel EP Impurity K (CAS 793-55-5)
- Levonorgestrel EP Impurity A (CAS 1260525-53-8)
Recommended Standards
- Etonogestrel EP Impurity D (CAS 54024-17-8)
- Ethyl 2-(3-methylthioureido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (CAS 51486-13-6)
- N,N-Diisopropyl-4-isothiocyanatobenzenesulfonamide (CAS 956576-76-4)
- 9-Undecylacridine (CAS 69202-35-3)
- Vortioxetine Impurity 111 (CAS 640767-44-8)
- Solriamfetol Impurity 23 (CAS CATO-C4X-256323)
- Roxatidine Impurity 17 (CAS CATO-C4X-121317)
- 4-(2-Methoxy-phenylcarbamoyl)-butyric acid (CAS 401629-34-3)
- Methyl 6,8-dibromo-2H-chromene-3-carboxylate (CAS 177496-81-0)
- tert-Butyl (3-carbamothioylbicyclo[1.1.1]pentan-1-yl)carbamate (CAS 2690365-97-8)
- 1H,1H,7H-Perfluoroheptan-1-ol (CAS 335-99-9)
- (5-Fluoro-3-methyl-1-benzofuran-2-yl)methanamine hydrochloride (CAS 1315365-09-3)
- Methyl 3-Methylisoxazole-4-carboxylate (CAS 92234-50-9)
- Insulin Degludec Impurity 9 (CAS CATO-C4X-21579)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com