5-{[3-(trifluoromethyl)phenoxy]methyl}furan-2-carboxylic acid CAS 74556-59-5
| CAS No. | 74556-59-5 |
| Molecular Formula | C13H9F3O4 |
| Molecular Weight | 286.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-{[3-(trifluoromethyl)phenoxy]methyl}furan-2-carboxylic acid (CAS 74556-59-5), molecular formula C13H9F3O4 and molecular weight 286.20 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-{[3-(trifluoromethyl)phenoxy]methyl}furan-2-carboxylic acid (C13H9F3O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-{[3-(trifluoromethyl)phenoxy]methyl}furan-2-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H9F3O4 |
| Molecular Weight | 286.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | F-containing |
Related trifluoromethyl Standards
- 1-((3-(Trifluoromethyl)phenoxy)methyl)-1H-pyrazole-3-carboxylic acid (CAS 1004193-05-8)
- 3-(5-(4-(Trifluoromethyl)phenyl)-1,3,4-oxadiazol-2-yl)propanoic acid (CAS 1179161-29-5)
- Ethyl 5-(3-(trifluoromethyl)phenyl)-1,3,4-oxadiazole-2-carboxylate (CAS 1432053-94-5)
- Ethyl 5-(4-(trifluoromethyl)phenyl)-[1,2,4]oxadiazole-3-carboxylate (CAS 151098-18-9)
- Ethyl 3-(4-(trifluoromethyl)phenyl)-1,2,4-oxadiazole-5-carboxylate (CAS 163719-82-2)
- Ethyl 5-(3-(trifluoromethyl)phenyl)-1,2,4-oxadiazole-3-carboxylate (CAS 163720-43-2)
- 2-{5-[3-(trifluoromethyl)phenyl]-2H-1,2,3,4-tetrazol-2-yl}acetohydrazide (CAS 729578-99-8)
- 3-(3-(3-(Trifluoromethyl)phenyl)-1,2,4-oxadiazol-5-yl)propanoic acid (CAS 866018-88-4)
Recommended Standards
- 5-(4-Methoxyphenyl)-2-(trifluoromethyl)furan-3-carboxylic acid (CAS 239080-02-5)
- 5-Phenylthiophene-2-boronic Acid Pinacol Ester (CAS 459409-74-6)
- 4,4,5,5-Tetramethyl-2-(4-phenyl-2-thienyl)-1,3,2-dioxaborolane (CAS 960116-25-0)
- 5-[(4-carboxyphenyl)diazenyl]-2-hydroxybenzoic acid (CAS 64896-26-0)
- 3-(2-amino-1-hydroxyethyl)benzonitrile hydrochloride (CAS 50916-54-6)
- n-Methyl-1-(6-(trifluoromethyl)pyridin-3-yl)methanamine (CAS 886364-80-3)
- Benzyl (3-hydroxy-2-methylpropyl)carbamate (CAS 1381761-65-4)
- 4-Methyl-5-nitro-2,6-di(piperidin-1-yl)pyrimidine (CAS 94320-78-2)
- (R)-5-Amino-2-(4-methylphenylsulfonamido)-5-oxopentanoic acid (CAS 883452-10-6)
- Ethyl 3-(2-fluorophenyl)-1,2,4-oxadiazole-5-carboxylate (CAS 1018125-37-5)
- 4-Chloro-butanoic Acid Ethyl Ester-d6 4-Chloro-butyric Acid Ethyl Ester-d6 927810-76-2 Ethyl 4-Chlorobutyrate-d6 Ethyl |A-Chlorobutyrate-d6 Ethyl |O-Chlorobutyrate-d6 NSC 81215-d6 (CAS 927810-76-2)
- methyl 2-{[(2-methylphenyl)methyl]amino}acetate hydrochloride (CAS 186202-99-3)
- Chlorprothixene EP Impurity B HCl (CAS 4907-84-0)
- Tirzepatide Impurity 22 X TFA Salt (CAS CATO-C4X-324022)
Why CATO?
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