4-Chloro-N,N-dimethylbenzenesulfonamide CAS 7463-22-1
| CAS No. | 7463-22-1 |
| Molecular Formula | C8H10ClNO2S |
| Molecular Weight | 219.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Chloro-N,N-dimethylbenzenesulfonamide (CAS 7463-22-1) is a high-purity analytical reference standard with the molecular formula C8H10ClNO2S and a molecular weight of 219.69 g/mol.
The molecular framework of 4-Chloro-N,N-dimethylbenzenesulfonamide (C8H10ClNO2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Chloro-N,N-dimethylbenzenesulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H10ClNO2S |
| Molecular Weight | 219.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
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Recommended Standards
- 4-Chloro-N-(5-methyl-1,3,4-thiadiazol-2-yl)butanamide (CAS 392244-44-9)
- 4-Chloro-N-ethylbenzenesulfonamide (CAS 6318-34-9)
- 4-Chloro-5-(((2-methylallyl)thio)methyl)isoxazol-3(2H)-one (CAS 89660-98-0)
- 5-Chloro-2-(ethanesulfonyl)aniline (CAS 873980-17-7)
- N-Methyl-2,3-difluorobenzylamine (CAS 906645-41-8)
- 5-Chloro-6-nitro-1H-indazole (CAS 101421-23-2)
- MLS 1547 (CAS 315698-36-3)
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- Methyl 2-(benzo[d]thiazole-6-carboxamido)benzo[d]thiazole-6-carboxylate (CAS 888409-17-4)
- 3-Amino-N-(3,4-dimethylphenyl)-4,6-diphenylthieno[2,3-b]pyridine-2-carboxamide (CAS 332040-37-6)
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- 2,8-Dichloro-tricyclo[8.2.2.24,7]hexadeca-4,6,10,12,13,15-hexaene (CAS 136002-57-8)
- Semaglutide impurity 55 (CAS CATO-C4X-222655)
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