2-(2-Bromo-4-fluorophenoxy)pyridine-3-carboxylic acid CAS 954563-46-3
| CAS No. | 954563-46-3 |
| Molecular Formula | C12H7BrFNO3 |
| Molecular Weight | 312.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(2-Bromo-4-fluorophenoxy)pyridine-3-carboxylic acid.
2-(2-Bromo-4-fluorophenoxy)pyridine-3-carboxylic acid (CAS 954563-46-3) is a high-purity analytical reference standard with the molecular formula C12H7BrFNO3 and a molecular weight of 312.09 g/mol.
The molecular framework of 2-(2-Bromo-4-fluorophenoxy)pyridine-3-carboxylic acid (C12H7BrFNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(2-Bromo-4-fluorophenoxy)pyridine-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H7BrFNO3 |
| Molecular Weight | 312.09 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
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Recommended Standards
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- Methyl 2-(3-(benzyloxy)pyridin-2-yl)acetate (CAS 848318-14-9)
- Semaglutide impurity 78 (CAS CATO-C4X-222678)
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