Pioglitazone Impurity 8 CAS 74772-78-4
| CAS No. | 74772-78-4 |
| Molecular Formula | C10H9NO3S |
| Molecular Weight | 223.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C10H9NO3S, Pioglitazone Impurity 8 contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 223.25 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Pioglitazone Impurity 8 (CAS 74772-78-4), a pharmacopoeial impurity reference standard (molecular formula C10H9NO3S, MW 223.25 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H9NO3S |
| Molecular Weight | 223.25 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Pioglitazone Standards
- Pioglitazone Impurity 15 (CAS 291536-42-0)
- Pioglitazone Impurity 19 (CAS 144809-26-7)
- Pioglitazone impurity 56 (CAS 1258625-43-2)
- Pioglitazone Impurity 23 (CAS CATO-C4X-138323)
- Pioglitazone Amino Impurity (CAS 85583-40-0)
- Pioglitazone Impurity 2 (CAS 69088-97-7)
- Pioglitazone Aldehyde Impurity (CAS 114393-97-4)
- Pioglitazone impurity 49 (CAS CATO-C4X-138349)
Recommended Standards
- Fasudil Impurity 69 (CAS CATO-C4X-136569)
- 4-Amino-1-naphthalenesulfonic Acid (CAS 84-86-6)
- Fasudil Impurity 57 (CAS 146257-38-7)
- 6-Amino-1-naphthalenesulfonic Acid (CAS 81-05-0)
- Vildagliptin Impurity 78 (CAS 2246354-69-6)
- Mivacurium Chloride Impurity 7 (S-S isomer) (CAS 104758-51-2)
- Carbasalate EP Impurity B (CAS 530-75-6)
- 2-(3-Hydroxyphenyl)ethanol (CAS 13398-94-2)
- 4-Chloro-N-(3-cyano-4-tosylphenyl)benzamide (CAS 320421-31-6)
- 4-bromo-2-(1H-1,2,4-triazol-1-yl)benzoic acid (CAS 1099687-28-1)
- 2-((5-(4-Fluorophenyl)-4-((tetrahydrofuran-2-yl)methyl)-4H-1,2,4-triazol-3-yl)thio)acetic acid (CAS 741731-81-7)
- Benzyl 2-bromo-4-chlorobutanoate (CAS 304909-62-4)
- 3-(2-(Aminomethyl)cyclopropyl)benzonitrile (CAS 1344255-37-3)
- Staphylococcus Aureus Protein A (SpA)-Derived Peptide (H-2228.0005) (CAS 144979-26-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com