2-Chloro-N-[3-cyano-4,5-bis(4-methoxyphenyl)furan-2-yl]acetamide CAS 748792-96-3
| CAS No. | 748792-96-3 |
| Molecular Formula | C21H17ClN2O4 |
| Molecular Weight | 396.82 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Chloro-N-[3-cyano-4,5-bis(4-methoxyphenyl)furan-2-yl]acetamide is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-Chloro-N-[3-cyano-4,5-bis(4-methoxyphenyl)furan-2-yl]acetamide (CAS 748792-96-3), a certified reference material (molecular formula C21H17ClN2O4, MW 396.82 g/mol) for analytical method development and quality control.
The molecular framework of 2-Chloro-N-[3-cyano-4,5-bis(4-methoxyphenyl)furan-2-yl]acetamide (C21H17ClN2O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Chloro-N-[3-cyano-4,5-bis(4-methoxyphenyl)furan-2-yl]acetamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H17ClN2O4 |
| Molecular Weight | 396.82 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 2-[2-(2-Chloro-6,7-dimethoxyquinolin-3-yl)ethyl]-1H-isoindole-1,3(2H)-dione (CAS 1105193-51-8)
- 2-(2-(2-Chloro-5,8-dimethoxyquinolin-3-yl)ethyl)isoindoline-1,3-dione (CAS 1105193-56-3)
- 3-Chloro-N-(1-(furan-2-ylmethyl)-2,5-dioxo-1,2,5,6,7,8-hexahydroquinolin-3-yl)benzamide (CAS 477864-94-1)
- 6-Chloro-2-oxo-N-[1-(phenylmethyl)-1H-pyrazol-5-yl]-3(2H)-benzoxazolepropanamide (CAS 1177727-04-6)
- 4-[(2-Chloro-6-fluorophenyl)methoxy]-N'-[(1E)-(4-methylphenyl)methylidene]benzohydrazide (CAS 303987-26-0)
- 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-3-methyl-4-[4-(propan-2-yl)phenyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 860785-30-4)
- 4-Chloro-N'-[3-(morpholine-4-sulfonyl)pyridin-2-yl]benzohydrazide (CAS 1774905-64-4)
- 4-Chloro-2-nitro-N-(2,2,4-trimethyl-2,3-dihydrobenzofuran-7-yl)benzenesulfonamide (CAS 866152-03-6)
Recommended Standards
- 3-(3-(4-Chlorophenyl)-5,9-dimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanoic acid (CAS 777857-53-1)
- 2-(4-Chlorophenyl)-4-methyl-N-[3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide (CAS 320420-80-2)
- Methyl 2-(4-(3-(4-chlorophenyl)ureido)phenoxy)benzoate (CAS 865660-46-4)
- 2-((N-Allyl-4-chloro-3-(trifluoromethyl)phenyl)sulfonamido)-N-cyclopropylacetamide (CAS 852941-46-9)
- SIpOMeMesCuCl (CAS 2271064-72-1)
- 4-(methylsulfanyl)pyrimidine-2-carboxylic acid (CAS 1211589-74-0)
- 4-(2-Fluorophenyl)-N-(4-methylphenyl)piperazine-1-carboxamide (CAS 710312-07-5)
- Ethyl 2,4-dibromobenzoate (CAS 438536-02-8)
- Methyl (4-chloro-2-methylphenyl)carbamate (CAS 22735-56-4)
- 3-(5-Bromopyrimidin-2-yl)aniline (CAS 1339681-12-7)
- 2,5-dimethoxy-4-nitrobenzaldehyde (CAS 1207-59-6)
- 4-Methyl-5-((3-methyl-1h-pyrazol-1-yl)methyl)-4h-1,2,4-triazole-3-thiol (CAS 1001567-70-9)
- 6-Hydroxy-2-methylnicotinic Acid (CAS 66909-37-3)
- Hepcidin/LEAP-1 (Human); Liver-Expressed Antimicrobial Peptide (CAS 342790-21-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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