4-Chloro-2-((2-chloro-5-(trifluoromethyl)phenyl)sulfonamido)benzoic acid CAS 749896-99-9
| CAS No. | 749896-99-9 |
| Molecular Formula | C14H8Cl2F3NO4S |
| Molecular Weight | 414.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Chloro-2-((2-chloro-5-(trifluoromethyl)phenyl)sulfonamido)benzoic acid (CAS 749896-99-9), molecular formula C14H8Cl2F3NO4S and molecular weight 414.18 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 4-Chloro-2-((2-chloro-5-(trifluoromethyl)phenyl)sulfonamido)benzoic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 414.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Chloro-2-((2-chloro-5-(trifluoromethyl)phenyl)sulfonamido)benzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H8Cl2F3NO4S |
| Molecular Weight | 414.18 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 4-Chloro-2-[4-chloro-3-(trifluoromethyl)benzenesulfonamido]benzoic acid (CAS 756851-01-1)
- (2E)-3-[5-Chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-1-(2-chloro-4-methylquinolin-3-yl)prop-2-en-1-one (CAS 400074-47-7)
- (E)-({1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-pyrrol-2-yl}methylidene)[(4-chlorophenyl)methoxy]amine (CAS 321430-81-3)
- 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-[(4-chlorophenyl)methyl]-1H-pyrrole-2-carboxamide (CAS 338397-61-8)
- 2,3-Bis[3-chloro-5-(trifluoromethyl)pyridin-2-yl]propanenitrile (CAS 246022-09-3)
- 2-Chloro-N-(2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)benzenesulfonamide (CAS 338409-38-4)
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Recommended Standards
- 2,4-Dichloro-5-{[3-(trifluoromethyl)phenyl]sulfamoyl}benzoic acid (CAS 21525-24-6)
- 3-[(4-bromophenyl)methyl]-1-methyl-7-(trifluoromethyl)-1h,2h,3h,4h-pyrido[2,3-d]pyrimidine-2,4-dione (CAS 1147522-06-2)
- Ethyl 5-(4-bromophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate (CAS 313249-39-7)
- 4-Methoxy-5-(tributylstannyl)pyrimidin-2-amine (CAS 597551-31-0)
- 4-Chloro-2-fluoro-3-propoxyphenylboronic acid (CAS 1256346-23-2)
- 1-(Pyridin-2-yl)-5,6,7,8-tetrahydroisoquinoline (CAS 871798-83-3)
- Diethyl 2-(2-formylphenyl)malonate (CAS 1353895-63-2)
- 2-(((1-Phenylethylidene)amino)oxy)acetic acid (CAS 1205-09-0)
- (1-(4-Methoxyphenyl)-4-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methanamine (CAS 690199-95-2)
- 3-(Ethoxycarbonyl)-5-methyl-1-(2-methylphenyl)-4,5-dihydro-1h-pyrazole-5-carboxylic acid (CAS 1264045-32-0)
- 1-(((2S,4S,5R)-4-(2,4-Difluorophenyl)-5-(2-tosylethyl)-1,3-dioxolan-2-yl)methyl)-1H-1,2,4-triazole (CAS 171764-49-1)
- 6-(Aminomethyl)-3-chloro-4-(difluoromethyl)pyridin-2-amine (CAS 1805327-18-7)
- 3-(5-(4-Methylphenyl)-1,3-oxazol-2-yl)propanoyl chloride (CAS 1023817-07-3)
- Neuropeptide Y (human, rat) trifluoroacetate salt (CAS 90880-35-6)
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