Bumetanide Impurity 104 CAS 751422-00-1
| CAS No. | 751422-00-1 |
| Molecular Formula | C13H9NO8S |
| Molecular Weight | 339.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Bumetanide Impurity 104 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Bumetanide Impurity 104 (CAS 751422-00-1, C13H9NO8S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Bumetanide Impurity 104 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 339.28 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C13H9NO8S |
| Molecular Weight | 339.28 g/mol |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Bumetanide Standards
- Bumetanide Impurity 51 (CAS CATO-C4X-198651)
- Bumetanide EP Impurity A (CAS 28328-53-2)
- Bumetanide Impurity 123 (CAS CATO-C4X-1986123)
- Bumetanide Impurity 124 (CAS CATO-C4X-1986124)
- Bumetanide Impurity 125 (CAS CATO-C4X-1986125)
- Bumetanide Impurity 136 (CAS CATO-C4X-1986136)
- Bumetanide Impurity 52 (CAS CATO-C4X-198652)
- Bumetanide Impurity 83 (CAS CATO-C4X-198683)
Recommended Standards
- N, N-Dinitroso Methotrexate EP Impurity L (CAS CATO-C4X-115446)
- tert-Butyl 4-(2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)ethyl)piperidine-1-carboxylate (CAS 2304833-67-6)
- 6-(Difluoromethoxy)-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid (CAS 121935-03-3)
- tert-Butyl 3,3-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate (CAS 2820191-55-5)
- Alprazolam impurity 21 (CAS 37945-06-5)
- Cefpodoxime Impurity 50 (CAS CATO-C4X-157950)
- Trazodone impurity 53 (CAS 1346603-99-3)
- 4-(Difluoromethyl)-3,6-diiodopyridin-2-ol (CAS 1805330-56-6)
- 3-Hydroxy-1-propylpiperidine (CAS 27361-79-1)
- 1-(4-((6,7-Dimethoxy-3,4-dihydroisoquinolin-1-yl)methyl)phenyl)-3-(4-(dimethylamino)phenyl)urea (CAS 1024361-27-0)
- 2-Fluoro-N-isopentylaniline (CAS 1019581-23-7)
- 6-Azaspiro[3.5]Nonan-2-ol (CAS 2167458-37-7)
- 8-fluoro-7-(hydroxymethyl)-3-methyl-1H-quinoxalin-2-one (CAS 2756334-27-5)
- Exenatide (CAS 141758-74-9（free base）)
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