Propyl[(thiophen-2-yl)methyl]amine CAS 751436-48-3
| CAS No. | 751436-48-3 |
| Molecular Formula | C8H13NS |
| Molecular Weight | 155.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Propyl[(thiophen-2-yl)methyl]amine is closely related to a nitrile group, sulfur-containing functionality in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Propyl[(thiophen-2-yl)methyl]amine (CAS 751436-48-3) is a high-purity analytical reference standard with the molecular formula C8H13NS and a molecular weight of 155.26 g/mol.
The molecular framework of Propyl[(thiophen-2-yl)methyl]amine (C8H13NS) is characterized by a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H13NS |
| Molecular Weight | 155.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Propyl Standards
- 2-methyl-3-(thiophen-2-yl)propan-1-amine (CAS 1017145-12-8)
- 2-(Thiophen-2-yl)butan-1-amine (CAS 1082507-14-9)
- (R)-1-(thiophen-3-yl)butan-1-amine (CAS 1212915-35-9)
- (S)-1-(thiophen-3-yl)butan-1-amine (CAS 1213084-04-8)
- (S)-1-(thiophen-2-yl)butan-1-amine (CAS 1213114-47-6)
- (R)-1-(thiophen-2-yl)butan-1-amine (CAS 1213586-78-7)
- 4-(Thiophen-3-yl)butan-1-amine (CAS 1341708-79-9)
- 2-Methyl-1-(thiophen-2-yl)propan-1-amine (CAS 56072-60-7)
Recommended Standards
- N,α-Dimethyl-3-thiopheneethanamine (CAS 857521-94-9)
- 21382-98-9 4-(methylthio)benzonitrile 4-methylsulfanylbenzenecarbonitrile A815302 (CAS 21382-98-9)
- N-(thiophen-3-ylmethyl)propan-2-amine (CAS 937667-50-0)
- 1-(thiophen-2-yl)butan-1-amine 473732-79-5 RTR-044137 (CAS 473732-79-5)
- 1-(3-Methyl-4-nitrophenyl)piperidine-2-carboxylic acid (CAS 1189547-44-1)
- n-(4-Amino-2-methylphenyl)thiophene-2-carboxamide (CAS 351424-40-3)
- 2-Amino-2-(5-methoxy(2-pyridyl))acetic acid (CAS 1499621-79-2)
- Diosmin EP Impurity A (CAS 6100-74-9)
- 2-Benzyl-2H-indazol-6-amine (CAS 1189475-11-3)
- 3-oxabicyclo[3.1.0]hexan-1-ylmethanamine;hydrochloride (CAS 2387597-55-7)
- Netupitant Impurity 3 (CAS CATO-C4X-12233)
- 6-Bromo-3-chloroquinoxalin-2-amine (CAS 1083181-47-8)
- 1-((5-(Diethylamino)pentan-2-yl)amino)-4-hydroxyanthracene-9,10-dione (CAS 69658-03-3)
- 59880-97-6 Chemotactic peptide F-Met-Leu-Phe L-Phenylalanine, N-(N-(N-formyl-L-methionyl)-L-leucyl)- N-Formyl-L-methionyl-L-leucyl-L-phenylalanine N-Formyl-Met-Leu-Phe N-Formylmethionine leucyl-phenylalanine fMLF fMLP (misnomer but widely used) (CAS 59880-97-6)
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