5-Hydroxy-2-phenyl-1-benzofuran-3-carboxylic acid CAS 75161-15-8
| CAS No. | 75161-15-8 |
| Molecular Formula | C15H10O4 |
| Molecular Weight | 254.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Hydroxy-2-phenyl-1-benzofuran-3-carboxylic acid (CAS 75161-15-8) is a high-purity analytical reference standard with the molecular formula C15H10O4 and a molecular weight of 254.24 g/mol.
Owing to a flavonoid core, a hydroxyl group, an ether linkage, 5-Hydroxy-2-phenyl-1-benzofuran-3-carboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 254.24 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Hydroxy-2-phenyl-1-benzofuran-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H10O4 |
| Molecular Weight | 254.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
Related Hydroxy Standards
- 7-Hydroxy-2-(3-hydroxyphenyl)-4H-chromen-4-one (CAS 108238-40-0)
- 1220030-02-3 4-[(2-Hydroxy-1,1-dimethylethyl)amino]-3-nitrobenzoic acid (CAS 1220030-02-3)
- (Z)-5-Hydroxy-2-(2-hydroxybenzylidene)benzofuran-3(2H)-one (CAS 1234351-46-2)
- 3-(5-Hydroxy-1H-indazol-1-yl)benzoic acid (CAS 1505748-16-2)
- (Z)-6-Hydroxy-2-(4-hydroxybenzylidene)benzofuran-3(2H)-one (CAS 5786-54-9)
- 1-Hydroxy-2-methoxyanthracene-9,10-dione (CAS 6003-11-8)
- 1-Hydroxy-4-methoxyanthracene-9,10-dione (CAS 7336-64-3)
- 1-Hydroxy-5-methoxyanthracene-9,10-dione (CAS 52869-21-3)
Recommended Standards
- 5-Ethyl-2,2'-anhydrouridine (CAS 72503-93-6)
- 5-Methyl-1-(quinolin-4-yl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 70292-13-6)
- 5-Benzyloxy-2-nitrobenzonitrile (CAS 38713-61-0)
- 5-Methyl-2-(4-nitrophenyl)benzo[d]oxazole (CAS 893-17-4)
- (S)-2-((1H-indol-3-yl)methyl)-3-((tert-butoxycarbonyl)amino)propanoic acid (CAS 1260608-35-2)
- 2-Methyl-5-nitropyrimidine (CAS 14080-34-3)
- Boc-β-HoArg(Pbf)-OH (CAS 1998216-44-6)
- N-Cyclopentyl-2-[[2-(4-Fluorophenyl)-7-Methyl-4-Quinazolinyl]Thio]-Acetamide (CAS 606132-71-2)
- n-{3-[(2-methoxyphenyl)sulfamoyl]-4-methylphenyl}cyclopropanecarboxamide (CAS 924138-80-7)
- 1-(P-tolyl)cyclohexan-1-amine hydrochloride (CAS 125802-03-1)
- Methyl (E)-4-(4-chlorophenyl)-4-oxobut-2-enoate (CAS 32149-26-1)
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- n-Hydroxydecanamide (CAS 2259-85-0)
- Neuropeptide K (human, porcine, rat) trifluoroacetate salt (CAS 96827-05-3)
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