Bicalutamide EP Impurity H CAS 2512198-58-0
| CAS No. | 2512198-58-0 |
| Molecular Formula | C18H14F4N2O4S |
| Molecular Weight | 430.37 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, Bicalutamide EP Impurity H is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 430.37 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a process- or degradation-related impurity, Bicalutamide EP Impurity H (CAS 2512198-58-0, C18H14F4N2O4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Bicalutamide EP Impurity H under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H14F4N2O4S |
| Molecular Weight | 430.37 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Bicalutamide Standards
- (S)-Bicalutamide (CAS 113299-38-0)
- Bicalutamide impurity A (CAS 113299-40-4)
- Bicalutamide EP Impurity B (CAS 1159977-36-2)
- Bicalutamide Impurity 5 (CAS 1166228-30-3)
- Bicalutamide (CAS 90357-06-5)
- (R)-Bicalutamide-d4 (CAS 1217826-87-3)
- Bicalutamide Impurity 28 (CAS CATO-C4X-101328)
- Bicalutamide USP Related Compound A (CAS 945419-64-7)
Recommended Standards
- Ac4ManNAz (CAS 361154-30-5)
- Ac4GalNAz (CAS 653600-56-7)
- Nicardipine Impurity 63 (CAS CATO-C4X-171063)
- 6-Methyl-2-oxo-2H-pyran-4-yl (2E)-3-(3-{[4-(trifluoromethyl)phenyl]methoxy}phenyl)prop-2-enoate (CAS 866151-68-0)
- Carbetocin Impurity 13 (CAS CATO-C4X-191113)
- Cefpirome Impurity 13 (CAS CATO-C4X-120713)
- Trazodone Impurity 66 (CAS CATO-C4X-177266)
- Regadenoson Impurity 56 (CAS CATO-C4X-198556)
- 4-Hydroxy-N1,N1,N2,N2-tetramethylphthalamide (CAS 1243440-20-1)
- 3-Cyclopropoxy-5-ethylpyridine-2-sulfonamide (CAS 1243393-19-2)
- (2Z)-1-(2H-1,3-Benzodioxol-5-yl)-3-[1-(1,3-thiazol-2-yl)-1H-pyrrol-2-yl]prop-2-en-1-one (CAS 866040-83-7)
- 2-Methyl-6-morpholinopyrimidin-4-amine (CAS 28732-85-6)
- (2,6-Bis(trifluoromethyl)quinolin-4-yl)methanol (CAS 1185292-81-2)
- 302798-54-5 (Leu31,Pro34)-Neuropeptide Y (13-36) (human, rat) MFCD00672463 (CAS 302798-54-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com