7-Chloro-3-methylbenzo[b]thiophene-2-carboxylic acid CAS 752135-41-4
| CAS No. | 752135-41-4 |
| Molecular Formula | C10H7ClO2S |
| Molecular Weight | 226.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 7-Chloro-3-methylbenzo[b]thiophene-2-carboxylic acid (C10H7ClO2S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 7-Chloro-3-methylbenzo[b]thiophene-2-carboxylic acid (CAS 752135-41-4), a certified reference material (molecular formula C10H7ClO2S, MW 226.68 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 7-Chloro-3-methylbenzo[b]thiophene-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H7ClO2S |
| Molecular Weight | 226.68 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 4-((4-Chloro-1H-pyrazol-1-yl)methyl)thiophene-2-carbaldehyde (CAS 1006493-41-9)
- 5-Chloro-3-(3-methoxyphenyl)-1,2,4-thiadiazole (CAS 1221341-41-8)
- 7-Chloro-1-cyclopropyl-6-fluoro-1,2,3,4-tetrahydroquinoxaline (CAS 1315469-43-2)
- 3-Chloro-7-methoxybenzo[b]thiophene-2-carbaldehyde (CAS 1315550-49-2)
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Recommended Standards
- 6-Chlorobenzo[b]thiophene-2-carbohydrazide (CAS 87999-22-2)
- Isopropyl (5-chloro-2-methylphenyl)carbamate (CAS 2621-68-3)
- 6-Chloro-3-methylbenzo[b]thiophene-2-carboxylic acid (CAS 66490-32-2)
- Methyl 3-chlorobenzo[b]thiophene-2-carboxylate (CAS 21211-07-4)
- Rhodotorulic acid (CAS 18928-00-2)
- 2-(2,4-Dimethylphenylsulfonamido)acetic acid (CAS 670255-96-6)
- 6-Chloro-3-phenylquinolin-2-ol (CAS 85274-64-2)
- PLAP (CAS 137314-60-4)
- 3-(2-(4-Methylpiperazin-1-yl)ethoxy)aniline (CAS 890652-00-3)
- N-(2-Chlorobenzyl)-4-(5-mercapto-1,3,4-oxadiazol-2-yl)benzenesulfonamide (CAS 917750-18-6)
- 1-(2,2-Dimethylbenzo[d][1,3]dioxol-5-yl)ethan-1-one (CAS 6860-95-3)
- (1-methanesulfonylcyclopentyl)methanamine hydrochloride (CAS 1803567-26-1)
- 2-(3-Chlorophenoxy)Propionamide (CAS 5825-87-6)
- Semaglutide Impurity 186 (CAS CATO-C4X-2226186)
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