2-(2-Chloro-3,4-dimethoxyphenyl)acetonitrile CAS 7537-07-7
| CAS No. | 7537-07-7 |
| Molecular Formula | C10H10ClNO2 |
| Molecular Weight | 211.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(2-Chloro-3,4-dimethoxyphenyl)acetonitrile is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-(2-Chloro-3,4-dimethoxyphenyl)acetonitrile (CAS 7537-07-7) is a high-purity analytical reference standard with the molecular formula C10H10ClNO2 and a molecular weight of 211.64 g/mol.
Structurally, 2-(2-Chloro-3,4-dimethoxyphenyl)acetonitrile (C10H10ClNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 211.64 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(2-Chloro-3,4-dimethoxyphenyl)acetonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H10ClNO2 |
| Molecular Weight | 211.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- 4-(2-(Cyclopropylmethoxy)ethyl)piperidine hydrochloride (CAS 1219967-17-5)
- 4-(Cyclohexylmethoxy)-1H-imidazo[4,5-c]pyridin-6-amine (CAS 872556-74-6)
- Difamilast Impurity 6 (CAS 937782-01-9)
- 6-((3,5-Dichlorophenyl)thio)-5-ethyl-1-((2-hydroxyethoxy)methyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (CAS 137897-90-6)
- Fibrinogen Related Peptide (CAS 80755-86-8)
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