Difamilast Impurity 6 CAS 937782-01-9
| CAS No. | 937782-01-9 |
| Molecular Formula | C24H26F2N2O5 |
| Molecular Weight | 460.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Difamilast Impurity 6 (CAS 937782-01-9, C24H26F2N2O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Difamilast Impurity 6 (C24H26F2N2O5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Difamilast Impurity 6 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H26F2N2O5 |
| Molecular Weight | 460.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difamilast Standards
- Difamilast Impurity 2 (CAS 2103190-94-7)
- Difamilast Impurity 4 (CAS 2103190-65-2)
- Difamilast (CAS 937782-05-3)
- Difamilast Impurity 11 (CAS 2103190-98-1)
- Difamilast Impurity 5 (CAS 2103190-81-2)
- Difamilast Impurity 8 (CAS 2103190-85-6)
- Difamilast Impurity 3 (CAS 937782-02-0)
- Difamilast Impurity 1 (CAS 1574285-40-7)
Recommended Standards
- Dihydroartemisinin O-β-D-glucuronide (CAS 198976-06-6)
- 1-(4-((6,7-Dimethoxy-3,4-dihydroisoquinolin-1-yl)methyl)phenyl)-3-(2-nitrophenyl)urea (CAS 1024068-70-9)
- 1-2-3-5-6-Penta-O-propanoyl-D-glucofuranose (CAS 307531-77-7)
- 1-2-3-Tri-O-benzoyl-4-deoxy-α-L-fucopyranose (CAS 132867-80-2)
- Trelagliptin Impurity 12 (CAS CATO-C4X-104612)
- Parecoxib Impurity 51 (CAS 2304623-35-4)
- Bicalutamide Impurity 29 (CAS CATO-C4X-101329)
- 7-Chloro-2,3-dihydro-1H-inden-1-ol (CAS 1215268-56-6)
- Paroxetine Impurity 55 (CAS 112058-89-6 (free base))
- 2,5-Dibromo-3-(bromomethyl)pyridine (CAS 61686-65-5)
- Zincformatedihydrate (CAS 5970-62-7)
- (1H-Pyrazol-5-yl)boronic acid (CAS 724710-02-5)
- 3-Chloro-4-(N,N-dimethylsulfamoyl)benzoic acid (CAS 1263276-33-0)
- Tirzepatide Impurity 49 (CAS CATO-C4X-324049)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com