2-Amino-3-(2-chloro-4-fluorophenyl)propanoic acid CAS 754152-25-5
| CAS No. | 754152-25-5 |
| Molecular Formula | C9H9ClFNO2 |
| Molecular Weight | 217.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-Amino-3-(2-chloro-4-fluorophenyl)propanoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-Amino-3-(2-chloro-4-fluorophenyl)propanoic acid (CAS 754152-25-5), molecular formula C9H9ClFNO2 and molecular weight 217.62 g/mol, is a CATO reference standard with documented purity and traceability.
2-Amino-3-(2-chloro-4-fluorophenyl)propanoic acid (C9H9ClFNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H9ClFNO2 |
| Molecular Weight | 217.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Amino Standards
- Ethyl 3-amino-6-chloro-2-fluorobenzoate (CAS 1103234-34-9)
- Ethyl 2-amino-4-chloro-3-fluorobenzoate (CAS 1108668-28-5)
- Ethyl 2-amino-3-chloro-5-fluorobenzoate (CAS 1179055-07-2)
- Ethyl 2-amino-6-chloro-3-fluorobenzoate (CAS 1184810-34-1)
- (R)-2-Amino-3-(2-chloro-4-fluorophenyl)propanoic acid (CAS 1212966-63-6)
- (S)-2-Amino-3-(2-chloro-4-fluorophenyl)propanoic acid (CAS 1213560-44-1)
- Methyl 2-amino-2-(2-chloro-6-fluorophenyl)acetate (CAS 1218388-17-0)
- Methyl 2-amino-2-(4-chloro-3-fluorophenyl)acetate (CAS 1249711-69-0)
Recommended Standards
- 2-{[(2-chloro-6-fluorophenyl)methyl]amino}acetic acid (CAS 926270-66-8)
- 2-Amino-3-(2-chloro-6-fluorophenyl)propanoic acid (CAS 603940-86-9)
- 2-((3-Chloro-4-fluorophenyl)amino)propanoic acid (CAS 52756-23-7)
- 2-Amino-3-(4-chloro-2-fluorophenyl)propanoic acid (CAS 754944-16-6)
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