3-Iodo-2-phenoxypyridine CAS 754214-57-8
| CAS No. | 754214-57-8 |
| Molecular Formula | C11H8INO |
| Molecular Weight | 297.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 297.09 g/mol gives 3-Iodo-2-phenoxypyridine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-Iodo-2-phenoxypyridine (CAS 754214-57-8) is a high-purity analytical reference standard with the molecular formula C11H8INO and a molecular weight of 297.09 g/mol.
The molecular framework of 3-Iodo-2-phenoxypyridine (C11H8INO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Iodo-2-phenoxypyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H8INO |
| Molecular Weight | 297.09 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Related Iodo Standards
- 3-iodo-4-nitro-1H-pyrrolo[2,3-b]pyridine (CAS 1000340-40-8)
- 3-iodo-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid (CAS 1221288-26-1)
- 4-Iodo-2-phenoxypyridine (CAS 1353776-69-8)
- 3-iodo-7-nitro-1H-indazole (CAS 864724-64-1)
- 5-Iodo-2-phenoxypyridine (CAS 352018-92-9)
- 5-Iodo-3-phenylpyrazin-2-amine (CAS 2090128-41-7)
- 3-Iodo-n-methylbenzenesulfonamide (CAS 1144522-75-7)
- 2-Iodo-N-methylbenzenesulfonamide (CAS 125259-03-2)
Recommended Standards
- 3-Bromo-6-methyl-4-(trifluoromethyl)isothiazolo[5,4-b]pyridine (CAS 296797-19-8)
- 2-(5-Fuoro-2-methoxy-3-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2782030-81-1)
- 2-(4-Fluoro-2-methoxy-5-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2488604-79-9)
- 951891-65-9 2-Bromo-3',4'-difluorobenzophenone MFCD09801524 (CAS 951891-65-9)
- 1-(Tert-butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid (CAS 40350-82-1)
- 5-Bromothiazole-2-carboxamide (CAS 957345-64-1)
- H-Lys(Z)-OH (CAS 1155-64-2)
- 2-(1H-Benzimidazol-2-yl)ethanamine 2-(1H-Benzimidazol-2-yl)ethylamine 4499-07-4 NSC67437 (CAS 4499-07-4)
- 2-Methyl-1,3,6-trioxocane (CAS 2781-01-3)
- Ibuprofen EP Impurity J (CAS 65813-55-0)
- N'-(6-Methyl-2-phenylquinolin-4-yl)isonicotinohydrazide (CAS 159586-80-8)
- (S)-3-amino-3-(4-bromophenyl)propanenitrile (CAS 1213162-44-7)
- Vildagliptin Impurity 101 (CAS CATO-C4X-1100101)
- Semaglutide Impurity 180 (CAS CATO-C4X-2226180)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com