N-[4-(chloromethyl)-1,3-thiazol-2-yl]-N-ethylacetamide CAS 757221-05-9
| CAS No. | 757221-05-9 |
| Molecular Formula | C8H11ClN2OS |
| Molecular Weight | 218.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-[4-(chloromethyl)-1,3-thiazol-2-yl]-N-ethylacetamide (C8H11ClN2OS) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies N-[4-(chloromethyl)-1,3-thiazol-2-yl]-N-ethylacetamide (CAS 757221-05-9), a certified reference material (molecular formula C8H11ClN2OS, MW 218.70 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H11ClN2OS |
| Molecular Weight | 218.70 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- 5-Cyclopropoxy-2-(dimethylamino)-N,N-dimethylnicotinamide (CAS 1243467-00-6)
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- 4,5-Dichloroaniline-2-sulfonic Acid (CAS 6331-96-0)
- Insulin Degludec impurity 4 (CAS CATO-C4X-21574)
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