Ethyl 5-chloro-3-(methylthio)-1,2,4-triazine-6-carboxylate, 97% CAS 75824-03-2
| CAS No. | 75824-03-2 |
| Molecular Formula | C7H8ClN3O2S |
| Molecular Weight | 233.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Ethyl 5-chloro-3-(methylthio)-1,2,4-triazine-6-carboxylate, 97% (CAS 75824-03-2) is a high-purity analytical reference standard with the molecular formula C7H8ClN3O2S and a molecular weight of 233.68 g/mol.
The molecular framework of Ethyl 5-chloro-3-(methylthio)-1,2,4-triazine-6-carboxylate, 97% (C7H8ClN3O2S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Ethyl 5-chloro-3-(methylthio)-1,2,4-triazine-6-carboxylate, 97% meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H8ClN3O2S |
| Molecular Weight | 233.68 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 5-Amino-2-(trifluoromethyl)oxazole-4-carbonitrile (CAS 907552-39-0)
- 2-((2-Amino-5-chloro-6-methylpyrimidin-4-yl)thio)acetic acid (CAS 338976-58-2)
- 4-Acetamidobenzenesulfonyl Chloride (CAS 121-60-8)
- Ticagrelor Impurity 61 (CAS CATO-C4X-109361)
- Ethyl 2-(2-aminoethyl)-6-oxo-1,6-dihydropyrimidine-5-carboxylate hydrochloride (CAS 1196154-49-0)
- 3-Chloro-N-(2,5-difluorophenyl)propanamide (CAS 915923-95-4)
- (S)-2-(3,5-bis(trifluoromethyl)benzyl)-3-((tert-butoxycarbonyl)amino)propanoic acid (CAS 1260590-43-9)
- N-[(3-Chlorophenyl)methyl]-N-(2-{N-[(3-chlorophenyl)methyl]4-methoxybenzenesulfonamido}ethyl)-4-methoxybenzene-1-sulfonamide (CAS 338775-09-0)
- Etomidate Impurity 44 (CAS 39096-80-5)
- 9-(4'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,1'-biphenyl]-3-yl)-9H-carbazole (CAS 1385826-87-8)
- 4-({[4-(trifluoromethyl)phenyl]amino}methyl)-1,2-dihydrophthalazin-1-one (CAS 305368-12-1)
- 3-(4-(3-Ethoxy-3-oxopropoxy)butoxy)propanoic acid (CAS 886362-91-0)
- Levothyroxine Impurity N90 (CAS 30804-52-5)
- Insulin Degludec Impurity 24 (CAS CATO-C4X-215724)
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