2-[3-(4-Chlorophenyl)-5-Fluorophenyl]Propanoic Acid CAS 75852-61-8
| CAS No. | 75852-61-8 |
| Molecular Formula | C15H12ClFO2 |
| Molecular Weight | 278.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-[3-(4-Chlorophenyl)-5-Fluorophenyl]Propanoic Acid (CAS 75852-61-8), molecular formula C15H12ClFO2 and molecular weight 278.71 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-[3-(4-Chlorophenyl)-5-Fluorophenyl]Propanoic Acid (C15H12ClFO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-[3-(4-Chlorophenyl)-5-Fluorophenyl]Propanoic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H12ClFO2 |
| Molecular Weight | 278.71 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | F/Cl-containing |
Related Chlorophenyl Standards
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