Edoxaban Impurity N1 CAS 758685-72-2
| CAS No. | 758685-72-2 |
| Molecular Formula | C8H10N2O2S |
| Molecular Weight | 198.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Edoxaban Impurity N1 (C8H10N2O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 198.24 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Edoxaban Impurity N1 (CAS 758685-72-2, C8H10N2O2S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Edoxaban Impurity N1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H10N2O2S |
| Molecular Weight | 198.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Edoxaban Standards
- Edoxaban impurity 129 (CAS CATO-C4X-1063129)
- Edoxaban Impurity 9 (CAS 552850-73-4)
- Edoxaban Impurity 11 (CAS 41374-72-5)
- Edoxaban Impurity 103 (CAS 929693-36-7)
- Edoxaban Impurity 110 (CAS CATO-C4X-1063110)
- Edoxaban impurity 133 (CAS CATO-C4X-1063133)
- Edoxaban Impurity 107 (CAS CATO-C4X-1063107)
- Edoxaban Impurity 113 (CAS CATO-C4X-1063113)
Recommended Standards
- Benzenesulfonic acid, 4-methyl-, ethenyl ester (CAS 83813-73-4)
- Ethyl 1,4,6,7-tetrahydrothiopyrano[4,3-c]pyrazole-3-carboxylate (CAS 912635-72-4)
- Barbituric Acid Impurity 19 (CAS 65959-54-8)
- Ethyl 1H,3H-thieno[3,4-c]furan-4-carboxylate (CAS 2103866-18-6)
- Suvorexant Impurity 17 (CAS 1293285-66-1)
- Nateglinide EP Impurity B (CAS 105816-05-5)
- Mizolastine Impurity 2 (CAS 935860-13-2)
- 6-Ethyl-2-((pyridin-2-ylmethyl)thio)pyrimidin-4(3H)-one (CAS 900007-89-8)
- Germacrene D (CAS 37839-63-7)
- 2-(5-Methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)ethyl 3-(trifluoromethyl)benzoate (CAS 860611-58-1)
- 3-Cyclohexyl-1,1-dimethylurea (CAS 31468-12-9)
- Pyridin-3-ylmethyl-(1,2,3,4-tetrahydro-naphthalen-1-yl)-amine hydrobromide (CAS 1052526-84-7)
- 1-(4-Chloro-5-fluoropyridin-3-yl)ethanone (CAS 1393563-13-7)
- [α-Glu](Sidechain trans-position)-Liraglutide (CAS CATO-C4X-199240)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com