3-Chloro-6-(trifluoromethyl)picolinic acid CAS 760147-01-1

Purity 97%+In StockPharmaceutical Standards
CAS No.760147-01-1
Molecular FormulaC7H3ClF3NO2
Molecular Weight225.55 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-Chloro-6-(trifluoromethyl)picolinic acid CAS 760147-01-1 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 225.55 g/mol gives 3-Chloro-6-(trifluoromethyl)picolinic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

3-Chloro-6-(trifluoromethyl)picolinic acid (CAS 760147-01-1) is a high-purity analytical reference standard with the molecular formula C7H3ClF3NO2 and a molecular weight of 225.55 g/mol.

The molecular framework of 3-Chloro-6-(trifluoromethyl)picolinic acid (C7H3ClF3NO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 3-Chloro-6-(trifluoromethyl)picolinic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC7H3ClF3NO2
Molecular Weight225.55 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1986
Halogen ContentF/Cl-containing
Nitrogen Atoms1

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