Mianserin EP Impurity E HCl CAS 76134-77-5
| CAS No. | 76134-77-5 |
| Molecular Formula | C17H18N2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Mianserin EP Impurity E HCl.
CATO supplies Mianserin EP Impurity E HCl (CAS 76134-77-5), a pharmacopoeial impurity reference standard (molecular formula C17H18N2HCl, MW 286.80 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, Mianserin EP Impurity E HCl is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 286.80 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Mianserin EP Impurity E HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H18N2 HCl |
| Molecular Weight | 286.80 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Mianserin Standards
- Mianserin impurity 02 (CAS 1074-11-9)
- Mianserin Impurity 91 (CAS 1192015-20-5)
- (±)-Mianserin-d3 Hydrochloride (methyl-d3) (CAS 1219804-97-3)
- Mianserin Impurity 80 (CAS 1260761-23-6)
- Mianserin Impurity 114 (CAS 1314960-88-7)
- Mianserin Impurity 102 HCl (CAS 131962-87-3)
- Mianserin impurity 43 (CAS 13665-04-8)
- Mianserin EP impurity B (CAS 140636-22-2)
Recommended Standards
- Niraparib Impurity 29 (CAS 2308483-85-2)
- Hydroxychloroquine Impurity 94 (CAS CATO-C4X-183594)
- Hydantoin Impurity 14 (CAS 99669-71-3)
- (R)-2-((tert-butoxycarbonyl)amino)-2-(3-fluorobicyclo[1.1.1]Pentan-1-yl)acetic acid (CAS 2201785-56-8)
- 7-Methyl[1,2,4]triazolo[3,4-b][1,3]benzothiazol-3-amine (CAS 105873-33-4)
- 1H-pyrazolo[3,4-b]pyridin-5-ol (CAS 1256818-99-1)
- Dexmedetomidine hydrochloride USP Impurity A (CAS 91874-85-0)
- 1-Bromo-3-difluoromethoxy-2-fluoro-6-nitrobenzene (CAS 1805525-05-6)
- 2-Ethyl-1-methyl-1H-benzo[d]imidazol-5-amine dihydrochloride (CAS 1158434-44-6)
- Antistasin-Related Peptide (CAS 161561-46-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com