2-[(2,5-Dichloro-4-pyrimidinyl)amino]-N-methylbenzenesulfonamide CAS 761440-11-3

Description

The molecular framework of 2-[(2,5-Dichloro-4-pyrimidinyl)amino]-N-methylbenzenesulfonamide (C11H10Cl2N4O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

2-[(2,5-Dichloro-4-pyrimidinyl)amino]-N-methylbenzenesulfonamide (CAS 761440-11-3), molecular formula C11H10Cl2N4O2S and molecular weight 333.19 g/mol, is a CATO reference standard with documented purity and traceability.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 2-[(2,5-Dichloro-4-pyrimidinyl)amino]-N-methylbenzenesulfonamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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