3-Methylenepyrrolidin-2-one CAS 76220-95-6

Purity 97%+In StockPharmaceutical Standards
CAS No.76220-95-6
Molecular FormulaC5H7NO
Molecular Weight97.12 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-Methylenepyrrolidin-2-one CAS 76220-95-6 chemical structure

Description

3-Methylenepyrrolidin-2-one (CAS 76220-95-6), molecular formula C5H7NO and molecular weight 97.12 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 3-Methylenepyrrolidin-2-one (C5H7NO) is characterized by an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 3-Methylenepyrrolidin-2-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC5H7NO
Molecular Weight97.12 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1978
Nitrogen Atoms1

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