3-(2-(Trifluoromethyl)phenoxy)azetidine CAS 76263-24-6
| CAS No. | 76263-24-6 |
| Molecular Formula | C10H10F3NO |
| Molecular Weight | 217.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(2-(Trifluoromethyl)phenoxy)azetidine.
3-(2-(Trifluoromethyl)phenoxy)azetidine (CAS 76263-24-6), molecular formula C10H10F3NO and molecular weight 217.19 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 3-(2-(Trifluoromethyl)phenoxy)azetidine (C10H10F3NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 217.19 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H10F3NO |
| Molecular Weight | 217.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethyl Standards
- 3-(5-Methyl-3-(trifluoromethyl)-1h-pyrazol-1-yl)butanenitrile (CAS 1006348-45-3)
- 2-(Trifluoromethyl)-5,6,7,8-tetrahydroquinazolin-4-amine (CAS 1017463-85-2)
- (S)-7-(trifluoromethyl)chroman-4-amine (CAS 1140496-05-4)
- (R)-8-(Trifluoromethyl)chroman-4-amine (CAS 1145685-65-9)
- 3-(3-(Trifluoromethyl)-1h-pyrazol-1-yl)pentanenitrile (CAS 1169970-91-5)
- 2-Methyl-7-(trifluoromethyl)-3,4-dihydro-2H-1,4-benzoxazine (CAS 1195534-16-7)
- (R)-7-(Trifluoromethyl)chroman-4-amine (CAS 1213657-96-5)
- (R)-6-(trifluoromethyl)chroman-4-amine (CAS 1228565-85-2)
Recommended Standards
- 2-Propyl-6-(trifluoromethyl)nicotinaldehyde (CAS 2204317-40-6)
- 3-(3-(Trifluoromethyl)phenoxy)azetidine (CAS 76263-23-5)
- 2,2,2-Trifluoro-N-phenethylacetamide (CAS 458-85-5)
- 3-(3-(Trifluoromethyl)phenyl)propanamide (CAS 535-53-5)
- 1-Tetradecanaminium, N-ethyl-N,N-dimethyl-, bromide (CAS 68527-84-4)
- Trimethyl(phenoxy)silane (CAS 1529-17-5)
- 4-(Butylamino)-7-chloroquinoline-3-carbonitrile (CAS 5423-71-2)
- Ethyl trans-4-ethoxycyclohexane-1-carboxylate (CAS 1067230-99-2)
- [1,2,3]triazolo[1,5-a]pyridin-4-amine (CAS 697739-18-7)
- 11-Hydroxy-2,3,4,11-tetrahydro-1H-10-oxa-5-azatetraphen-1-one (CAS 78831-30-8)
- Diethyl 2-(6-Methoxy-3-pyridyl)malonate (CAS 902130-84-1)
- 3-(((4-Chlorophenyl)imino)methyl)benzo[c]thiophen-1-ol (CAS 338954-45-3)
- Alprazolam Impurity 26 (CAS CATO-C4X-146026)
- Semaglutide impurity 289 (CAS CATO-C4X-2226289)
Why CATO?
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