2,4-Dichloro-5-(chloromethyl)pyrimidine CAS 7627-38-5
| CAS No. | 7627-38-5 |
| Molecular Formula | C5H3Cl3N2 |
| Molecular Weight | 197.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2,4-Dichloro-5-(chloromethyl)pyrimidine.
2,4-Dichloro-5-(chloromethyl)pyrimidine (CAS 7627-38-5), molecular formula C5H3Cl3N2 and molecular weight 197.45 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrile group, chlorine substitution, 2,4-Dichloro-5-(chloromethyl)pyrimidine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 197.45 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2,4-Dichloro-5-(chloromethyl)pyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H3Cl3N2 |
| Molecular Weight | 197.45 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1959 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichloro Standards
- 4,5-Dichloro-6-(chloromethyl)-pyrimidine (CAS 105708-06-3)
- 4,6-Dichloro-5-(chloromethyl)pyrimidine (CAS 1260790-15-5)
- 3,5-Dichloro-2-(chloromethyl)pyrazine (CAS 1824441-19-1)
- 4,6-Dichloro-2-(chloromethyl)pyrimidine (CAS 19875-05-9)
- 2,8-dichloro-9H-purine (CAS 89166-91-6)
- 3,6-dichloro-[1,2,4]triazolo[4,3-b]pyridazine (CAS 33050-38-3)
- 3,6-dichloro-1H-pyrazolo[3,4-d]pyrimidine (CAS 2089315-59-1)
- 3,5-Dichloro-4-fluorobenzenethiol (CAS 1160573-86-3)
Recommended Standards
- 2,4,6-Trichloropyridin-3-amine (CAS 91872-08-1)
- 2,5,6-Trichloropyridin-3-amine (CAS 55304-76-2)
- 2,4,5-Trichloro-6-methylpyrimidine (CAS 6554-69-4)
- 3,4,5-Trichloro-6-methylpyridazine (CAS 66572-23-4)
- 5-Fluoropyrimidine-2,4,6-triol (CAS 767-80-6)
- Methylsynephrine (CAS 365-26-4)
- 3-(Cyclohexyloxy)-2-(dimethylamino)phenol (CAS 1243279-99-3)
- Benzyltriethylphosphonium chloride (CAS 23666-92-4)
- (2R,4R)-1-tert-butoxycarbonyl-4-fluoro-pyrrolidine-2-carboxylic acid (CAS 681128-51-8)
- 2-(2,4-Diamino-5-(difluoromethyl)pyridin-3-yl)acetic acid (CAS 1805281-58-6)
- 6-Chloro-5-iodo-2-methylpyrimidin-4-amine (CAS 1770799-32-0)
- Tert-butyl 3-(2-aminoethoxy)piperidine-1-carboxylate (CAS 1353987-73-1)
- (2S)-1-[(pyridin-2-yl)carbonyl]pyrrolidine-2-carboxylic acid (CAS 167868-25-9)
- Peptide Impurity 64 (CAS CATO-CPTD788964)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com