5-Bromo-3-hydroxy-3-(2-oxopropyl)indolin-2-one CAS 76325-66-1
| CAS No. | 76325-66-1 |
| Molecular Formula | C11H10BrNO3 |
| Molecular Weight | 284.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Bromo-3-hydroxy-3-(2-oxopropyl)indolin-2-one.
5-Bromo-3-hydroxy-3-(2-oxopropyl)indolin-2-one (CAS 76325-66-1), molecular formula C11H10BrNO3 and molecular weight 284.11 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Bromo-3-hydroxy-3-(2-oxopropyl)indolin-2-one (C11H10BrNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-Bromo-3-hydroxy-3-(2-oxopropyl)indolin-2-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H10BrNO3 |
| Molecular Weight | 284.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 3-Bromo-4-nitro-6-isopropyl (1H)Indazole (CAS 1000340-89-5)
- 5-Bromo-1-(2-methoxyethyl)-2,3-dihydro-1h-indole-2,3-dione (CAS 1020974-19-9)
- 6-Bromo-1-(2-methoxyethyl)-2,3-dihydro-1h-indole-2,3-dione (CAS 1020994-26-6)
- 4-Bromo-7-ethoxy-1H-indole-2-carboxylic acid (CAS 1098340-08-9)
- 8-Bromo-5-hydroxy-4-(2-hydroxyethyl)quinolin-2-one (CAS 1155270-69-1)
- 7-Bromo-N-ethoxybenzofuran-2-carboxamide (CAS 1208690-20-3)
- Methyl 2-(6-bromo-5-methyl-3H-imidazo[4,5-b]pyridin-2-yl)acetate (CAS 1211507-06-0)
- 4-Bromo-6,7-dimethoxyisoquinolin-1(2H)-one (CAS 1211580-83-4)
Recommended Standards
- 5-Bromo-2-[(cyclopropylcarbonyl)amino]benzoic Acid (CAS 401462-74-6)
- 5-Bromo-4,7-dimethoxy-1H-indole-3-carbaldehyde (CAS 2410249-79-3)
- 5-Amino-4-bromo-pyrazolo[1,5-a]pyridine-3-carboxylic acid ethyl ester (CAS 2407051-37-8)
- 5-Bromo-N-methoxy-N-methyl-1H-indazole-3-carboxamide (CAS 936132-60-4)
- 2-(Furan-3-yl)-n-methylpyrimidin-4-amine (CAS 1342977-15-4)
- Ezetimibe Impurity 47 (CAS 1443306-85-1)
- N-(6-Methyl-2,3-dihydro-4H-thiochromen-4-yliden)-N-[(phenylsulfonyl)oxy]amine (CAS 383146-45-0)
- (R)-Methyl 3-hydroxy-3,4-dihydro-2H-pyrrole-5-carboxylate (CAS 114046-87-6)
- N-(3,4-dihydro-2H-pyrrol-5-yl)-5-methyl-1,3,4-thiadiazol-2-amine (CAS 753466-16-9)
- tert-Butyl 4-hydroxyiminopiperidine-1-carboxylate (CAS 150008-24-5)
- 3-Chloro-5-cyclopropoxy-N-methylpicolinamide (CAS 1243377-34-5)
- 2-hydroxy-2-(oxolan-3-yl)acetamide (CAS 1247174-57-7)
- (2-Amino-4-(trifluoromethyl)thiazol-5-yl)methanol (CAS 1314977-20-2)
- Semaglutide Impurity 115 (CAS CATO-C4X-2226115)
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