5-Chloro-3-hydroxy-3-(2-oxopropyl)indolin-2-one CAS 76325-67-2

Description

The occurrence of 5-Chloro-3-hydroxy-3-(2-oxopropyl)indolin-2-one is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

5-Chloro-3-hydroxy-3-(2-oxopropyl)indolin-2-one (CAS 76325-67-2), molecular formula C11H10ClNO3 and molecular weight 239.66 g/mol, is a CATO reference standard with documented purity and traceability.

5-Chloro-3-hydroxy-3-(2-oxopropyl)indolin-2-one (C11H10ClNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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