Azithromycin EP Impurity O CAS 763924-54-5
| CAS No. | 763924-54-5 |
| Molecular Formula | C39H74N2O12 |
| Molecular Weight | 763.01 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Azithromycin EP Impurity O (C39H74N2O12) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Azithromycin EP Impurity O (CAS 763924-54-5, C39H74N2O12) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Azithromycin EP Impurity O meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C39H74N2O12 |
| Molecular Weight | 763.01 g/mol |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 2 |
Related Azithromycin Standards
- Azithromycin N-Ethyl (CAS 92594-45-1)
- Azithromycin EP Impurity K (CAS 612534-95-9)
- Azithromycin EP Impurity F (CAS 612069-28-0)
- Azithromycin impurity 57 (CAS CATO-C4X-100357)
- Azithromycin EP Impurity L (CAS 90503-06-3)
- Azithromycin EP Impurity D (CAS 612069-26-8)
- Azithromycin impurity 58 (CAS CATO-C4X-100358)
- Azithromycin Impurity 28 (CAS CATO-C4X-100328)
Recommended Standards
- 4-(2,5-Dimethylpyrrolidin-1-yl)morpholine (CAS 6966-91-2)
- 2-[Bis[3,5-bis(1,1-dimethylethyl)phenyl]phosphino]-N-[2-[(3aR,8aS)-3a,8a-dihydro-8H-indeno[1,2-d]oxazol-2-yl]phenyl]benzamide (CAS 2762032-31-3)
- Treprostinil Impurity 4 (CAS CATO-C4X-21164)
- (SP-5-12)-Chloro[5,10,15,20-tetraphenyl-21H,23H-porphinato(2-)-κN21,κN22,κN23,κN24]indium (CAS 63128-70-1)
- Daprodustat Impurity 21 (CAS 918641-99-3)
- Ciprofloxacin Impurity 49 (CAS CATO-C4X-136249)
- Ozenoxacin Impurity 31 (CAS CATO-C4X-279631)
- 2-Chloro-n-(4-chloro-2-methylphenyl)propanamide (CAS 1016852-56-4)
- Sodium (4,5-dimethyl-1,2,4-triazol-3-yl)sulfanide (CAS 96008-33-2)
- 2-Methoxy-4-(methylthio)aniline (CAS 1657-84-7)
- 3-(3-Fluoro-4-methylphenyl)-2-oxopropanoic acid (CAS 1339480-89-5)
- 4-(5-Bromopyridin-2-yl)benzaldehyde (CAS 910547-57-8)
- 4,5-Dihydrofuran-3-carboxylic Acid (CAS 98021-62-6)
- Semaglutide impurity 202 (CAS CATO-C4X-2226202)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com