Treprostinil Impurity 4 CAS CATO-C4X-21164
| CAS No. | CATO-C4X-21164 |
| Molecular Formula | C46H66O9 |
| Molecular Weight | 763.01 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Treprostinil Impurity 4 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Treprostinil Impurity 4 (CAS CATO-C4X-21164, C46H66O9) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Treprostinil Impurity 4 (C46H66O9) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C46H66O9 |
| Molecular Weight | 763.01 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Treprostinil Standards
- Treprostinil Impurity 5 (CAS CATO-C4X-21165)
- Treprostinil Impurity 14 (CAS CATO-C4X-211614)
- Treprostinil Impurity 7 (CAS 1345337-82-7)
- Treprostinil Ethyl Ester (CAS 1355990-07-6)
- Treprostinil Methyl Ester (CAS 81845-98-9)
- Treprostinil-d9 (CAS 81846-19-7(non-labelled))
- Treprostinil (CAS 81846-19-7)
- Treprostinil Impurity 10 (CAS 1911575-29-5)
Recommended Standards
- Azithromycin N-Ethyl (CAS 92594-45-1)
- Azithromycin EP Impurity O (CAS 763924-54-5)
- Iopamidol EP Impurity B (CAS 77868-41-8)
- 4-(2,5-Dimethylpyrrolidin-1-yl)morpholine (CAS 6966-91-2)
- Loxoprofen Impurity 66 (CAS 334948-52-6)
- Afoxolaner Impurity 22 (CAS 1125812-56-7)
- Sotagliflozin Impurity 9 (CAS CATO-C4X-30049)
- 2-Hydroxy-3-isopropyl-6-methylbenzoic acid (CAS 548-51-6)
- 5-Chloro-2-(thiophen-2-yl)pyridine (CAS 56421-70-6)
- Methyl 4-(azetidine-3-carbonyl)benzoate (CAS 1823548-09-9)
- 4-Bromo-5,7-difluoroquinoline (CAS 1189107-48-9)
- 2-Cyclopropyl-6-oxo-1,6-dihydropyridine-3-carbonitrile (CAS 1774901-03-9)
- 2-(5-Methyl-1,3,4-oxadiazol-2-yl)benzofuran-4-ol (CAS 310390-91-1)
- Neuropeptide GE (CAS 134748-04-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com