6-Bromo-2h-[1,3]dioxolo[4,5-b]pyridine CAS 76470-56-9
| CAS No. | 76470-56-9 |
| Molecular Formula | C6H4BrNO2 |
| Molecular Weight | 202.01 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Bromo-2h-[1,3]dioxolo[4,5-b]pyridine.
CATO supplies 6-Bromo-2h-[1,3]dioxolo[4,5-b]pyridine (CAS 76470-56-9), a certified reference material (molecular formula C6H4BrNO2, MW 202.01 g/mol) for analytical method development and quality control.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system, 6-Bromo-2h-[1,3]dioxolo[4,5-b]pyridine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 202.01 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-Bromo-2h-[1,3]dioxolo[4,5-b]pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H4BrNO2 |
| Molecular Weight | 202.01 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 2-Bromo-3-hydroxyisonicotinaldehyde (CAS 1047665-64-4)
- 2-Bromo-5-hydroxyisonicotinaldehyde (CAS 1196145-13-7)
- 5-Bromo-2-hydroxyisonicotinaldehyde (CAS 1227562-37-9)
- 5-Bromo-3-hydroxypicolinaldehyde (CAS 1227582-97-9)
- 5-Bromo-2-oxo-1,2-dihydropyridine-3-carbaldehyde (CAS 1227603-42-0)
- 3-Bromo-5-hydroxypicolinaldehyde (CAS 1256813-46-3)
- 7-Bromo-[1,3]dioxolo[4,5-b]pyridine (CAS 1260663-83-9)
- 6-Bromo-4-hydroxypyridine-3-carbaldehyde (CAS 1260665-55-1)
Recommended Standards
- 5-Bromopyrimidine-2-carboxamide (CAS 38275-60-4)
- N-(2-Bromopyrimidin-5-yl)formamide (CAS 56621-86-4)
- 5-Bromopyridine-2-carboxylic Acid (CAS 30766-11-1)
- 1-Bromo-4-nitrobenzene (CAS 586-78-7)
- Ammonium 2-(3-ethylureido)-2-oxoacetate (CAS 105918-81-8)
- (2S,3S,4S)-2,3,4,6-Tetrahydroxy-5-oxohexanoic acid (CAS 13425-76-8)
- 2-(4-(Methylthio)phenyl)quinoline-4-carboxylic acid (CAS 351065-46-8)
- 4-Methyl-2-nitroquinoline (CAS 32110-63-7)
- 25475-67-6 3-isoquinolinamine InChI=1/C9H8N2/c10-9-5-7-3-1-2-4-8(7)6-11-9/h1-6H,(H2,10,11 isoquinolin-3-amine (CAS 25475-67-6)
- 2,6-Diamino-5-(difluoromethyl)nicotinaldehyde (CAS 1805236-26-3)
- 1-(3,4-Dimethylphenyl)ethane-1-thiol (CAS 1092300-17-8)
- 2-Hexadecanone (CAS 18787-63-8)
- 3-Benzyl-6-{[3-(3,4,5-trimethoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl}-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one (CAS 1040655-10-4)
- Myristoyl Pentapeptide -4 acetate (CAS 959610-30-1(free base))
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