3-Chloro-4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)aniline CAS 76471-06-2
| CAS No. | 76471-06-2 |
| Molecular Formula | C12H7Cl2F3N2O |
| Molecular Weight | 323.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-Chloro-4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)aniline is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-Chloro-4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)aniline (CAS 76471-06-2), molecular formula C12H7Cl2F3N2O and molecular weight 323.10 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-Chloro-4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)aniline (C12H7Cl2F3N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Chloro-4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)aniline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H7Cl2F3N2O |
| Molecular Weight | 323.10 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 3-Chloro-2-[(4-chloro-2-methylpyridin-3-yl)oxy]-5-(trifluoromethyl)pyridine (CAS 400075-75-4)
- 4-Chloro-3-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)aniline (CAS 87170-48-7)
- 1-(5-chloro-1-benzofuran-2-yl)-2-(2-chloro-4-fluorophenyl)ethan-1-one (CAS 1778933-17-7)
- 1000576-57-7 Benzyl 2-chloro-2-[2-(4-chlorophenyl)hydrazono]acetate MFCD09877991 (CAS 1000576-57-7)
- 2-Chloro-1-[3-(4-chlorophenyl)-5-(furan-2-yl)-4,5-dihydro-1h-pyrazol-1-yl]ethan-1-one (CAS 380196-88-3)
- 3-{5-chloro-2-[(2-chlorophenyl)methoxy]phenyl}prop-2-enoic acid (CAS 938341-14-1)
- 3-{5-Chloro-2-[(4-chlorophenyl)methoxy]-phenyl}prop-2-enoic acid (CAS 938233-04-6)
- 3-Chloro-2-(3-chloro-4-methoxyphenyl)-5-methoxy-2H-indazole (CAS 848142-50-7)
Recommended Standards
- 4-(3,4-Dichlorophenyl)-2-hydrazinyl-6-(trifluoromethyl)pyrimidine (CAS 862658-93-3)
- 3,5-Dichloro-4-((5-(trifluoromethyl)pyridin-2-yl)oxy)aniline (CAS 73265-16-4)
- 3,5-Dichloro-4-((3-(trifluoromethyl)pyridin-2-yl)oxy)aniline (CAS 1227955-22-7)
- 4-Pyrrolidinosulfonyl-2-trifluoromethylphenylboronic acid (CAS 2096338-19-9)
- 1-(4-Fluoro-2-methyl-3-nitrophenyl)ethanone (CAS 1806375-55-2)
- 1,2,3-Propanetricarbonitrile (CAS 62872-44-0)
- 2-(1H-Benzo[d][1,2,3]triazol-1-yl)-2-methylpropanoic acid (CAS 4233-61-8)
- 3,3',3'',3'''-(((1,2-Phenylenebis(oxy))bis(ethane-2,1-diyl))bis(azanetriyl))tetrakis(1-((9H-carbazol-4-yl)oxy)propan-2-ol) (CAS 1391052-20-2)
- 2-Piperidylacetic Acid (CAS 19832-04-3)
- Difelikefalin Impurity 4 (CAS 1173664-52-2)
- Elastin from pig (CAS 9007-58-3)
- (S)-6-((S)-2-hydroxy-6-methylhept-5-en-2-yl)-3-methylcyclohex-2-en-1-one (CAS 95602-94-1)
- 1-(6-Bromopyridin-3-yl)-2-methylpropan-2-amine (CAS 1393551-95-5)
- Peptide 440 (CAS CATO-CPTD788440)
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