4-Chloro-3-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)aniline CAS 87170-48-7
| CAS No. | 87170-48-7 |
| Molecular Formula | C12H7Cl2F3N2O |
| Molecular Weight | 323.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Chloro-3-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)aniline (CAS 87170-48-7), molecular formula C12H7Cl2F3N2O and molecular weight 323.10 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Chloro-3-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)aniline (C12H7Cl2F3N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Chloro-3-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)aniline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H7Cl2F3N2O |
| Molecular Weight | 323.10 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 3-Chloro-2-[(4-chloro-2-methylpyridin-3-yl)oxy]-5-(trifluoromethyl)pyridine (CAS 400075-75-4)
- 3-Chloro-4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)aniline (CAS 76471-06-2)
- 1-(5-chloro-1-benzofuran-2-yl)-2-(2-chloro-4-fluorophenyl)ethan-1-one (CAS 1778933-17-7)
- 1000576-57-7 Benzyl 2-chloro-2-[2-(4-chlorophenyl)hydrazono]acetate MFCD09877991 (CAS 1000576-57-7)
- 2-Chloro-1-[3-(4-chlorophenyl)-5-(furan-2-yl)-4,5-dihydro-1h-pyrazol-1-yl]ethan-1-one (CAS 380196-88-3)
- 3-{5-chloro-2-[(2-chlorophenyl)methoxy]phenyl}prop-2-enoic acid (CAS 938341-14-1)
- 3-{5-Chloro-2-[(4-chlorophenyl)methoxy]-phenyl}prop-2-enoic acid (CAS 938233-04-6)
- 3-Chloro-2-(3-chloro-4-methoxyphenyl)-5-methoxy-2H-indazole (CAS 848142-50-7)
Recommended Standards
- 4-(3,4-Dichlorophenyl)-2-hydrazinyl-6-(trifluoromethyl)pyrimidine (CAS 862658-93-3)
- 4-Pyrrolidinosulfonyl-2-trifluoromethylphenylboronic acid (CAS 2096338-19-9)
- 5-Bromo-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione (CAS 3370-69-2)
- 7-(4-Bromophenyl)-3-hydroxyfuro[3,2-d]pyrimidine-2,4(1H,3H)-dione (CAS 824984-01-2)
- 7-Nitropyrido[2,3-b]pyrazine (CAS 1337880-33-7)
- O-Acetylsalicyloyl Chloride (CAS 5538-51-2)
- 1-(2-Aminophenyl)-3-(2-chlorophenyl)propan-1-one (CAS 1313201-61-4)
- N-Methyl-N-(m-tolyl)pyrrolidine-2-carboxamide (CAS 1491331-76-0)
- 5-Methyl-6,7-dihydro-2H-pyrrolo[3,4-c]pyridin-4(5H)-one (CAS 358732-62-4)
- Ethyl6,6-difluoro-7-oxo-4,5-dihydro-1h-indole-2-carboxylate (CAS 1433990-09-0)
- 2-Chloro-8-(trifluoromethyl)quinolin-4-amine (CAS 1708160-46-6)
- 3-(2-Methylcyclopropyl)-1h-pyrazol-5-amine (CAS 1187765-24-7)
- 2-(4-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)oxazole (CAS 945226-59-5)
- Gastric Inhibitory Polypeptide (6-30) amide (human) (CAS 1139691-72-7)
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