7-(Trifluoromethyl)-1,2,3,4-tetrahydro-2,6-naphthyridine CAS 765298-22-4
| CAS No. | 765298-22-4 |
| Molecular Formula | C9H9F3N2 |
| Molecular Weight | 202.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
7-(Trifluoromethyl)-1,2,3,4-tetrahydro-2,6-naphthyridine (CAS 765298-22-4), molecular formula C9H9F3N2 and molecular weight 202.18 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C9H9F3N2, 7-(Trifluoromethyl)-1,2,3,4-tetrahydro-2,6-naphthyridine contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 202.18 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H9F3N2 |
| Molecular Weight | 202.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Trifluoromethyl Standards
- 1-(4-(Trifluoromethyl)pyridin-2-yl)cyclopropan-1-amine (CAS 1060805-56-2)
- 1-(6-(Trifluoromethyl)pyridin-2-yl)cyclopropan-1-amine (CAS 1060810-96-9)
- 1-(2-(Trifluoromethyl)pyridin-4-yl)cyclopropanamine (CAS 1060810-99-2)
- 3-(Trifluoromethyl)-6,7-dihydro-5H-cyclopenta[b]pyridin-5-amine (CAS 1196151-75-3)
- 6-(Trifluoromethyl)-1,2,3,4-tetrahydro-2,7-naphthyridine (CAS 1196155-32-4)
- 2-(Trifluoromethyl)-6,7-dihydro-5H-cyclopenta[b]pyridin-5-amine (CAS 1196156-85-0)
- 5-(Trifluoromethyl)-1,2,3,4-tetrahydro-2,6-naphthyridine (CAS 1211523-85-1)
- 7-(Trifluoromethyl)-1,2,3,4-tetrahydro-1,5-naphthyridine (CAS 1211525-01-7)
Recommended Standards
- 6-Cyclopropyl-5-(trifluoromethyl)pyridin-3-amine (CAS 2504231-24-5)
- 7-Fluoro-2h,3h,5h-indeno[1,2-c]pyridazin-3-one (CAS 81198-18-7)
- 6-(Trifluoromethyl)isoindolin-5-amine (CAS 905273-62-3)
- 8-Fluoro-4-hydroxy-6-methylquinoline-3-carbonitrile (CAS 61338-24-7)
- 1-(2,5-Dimethoxyphenyl)-2-azidoethanone (CAS 329039-62-5)
- N-(2-Indol-3-ylethyl)benzamide (CAS 4753-09-7)
- 2-Bromo-3-(bromomethyl)quinoline (CAS 35740-83-1)
- N4,N4'-Bis(4-(2,2-diphenylvinyl)phenyl)-N4,N4'-diphenyl-[1,1'-biphenyl]-4,4'-diamine (CAS 218598-81-3)
- 1-(4-Bromophenyl)-2-(3-hydroxypiperidin-1-yl)ethan-1-one (CAS 1458491-13-8)
- 2-(acetyloxy)-3,3,3-trifluoropropanoic acid (CAS 156816-81-8)
- (S)-2-(2-chlorobenzyl)pyrrolidine-2-carboxylic acid hydrochloride (CAS 637020-76-9)
- 5-Bromo-4-methyl-1-(4-((7-methyl-2-propyl-3H-imidazo[4,5-b]pyridin-3-yl)methyl)phenyl)-1H-pyrrole-2-carbonitrile (CAS 142016-06-6)
- Rosuvastatin Impurity 177 (CAS CATO-C4X-1169177)
- Acetyl-Tau Peptide (273-284) amide trifluoroacetate salt (CAS 1684399-52-7)
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