5,6-Dichloropyrazine-2-carboxylic acid CAS 76537-42-3
| CAS No. | 76537-42-3 |
| Molecular Formula | C5H2Cl2N2O2 |
| Molecular Weight | 192.99 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 192.99 g/mol gives 5,6-Dichloropyrazine-2-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5,6-Dichloropyrazine-2-carboxylic acid (CAS 76537-42-3), molecular formula C5H2Cl2N2O2 and molecular weight 192.99 g/mol, is a CATO reference standard with documented purity and traceability.
5,6-Dichloropyrazine-2-carboxylic acid (C5H2Cl2N2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5,6-Dichloropyrazine-2-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H2Cl2N2O2 |
| Molecular Weight | 192.99 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichloropyrazine Standards
- 3,5-Dichloropyrazine-2-carboxylic Acid (CAS 312736-49-5)
- 3,6-Dichloropyrazine-2-carboxylic acid (CAS 356783-15-8)
- 3,5-Dichloropyrazine-2-carboxamide (CAS 312736-50-8)
- 3,5-Dichloropyrazine-2-methanol (CAS 313339-89-8)
- Methyl 5,6-dichloropyrazine-2-carboxylate (CAS 1802251-49-5)
- Methyl 3,5-dichloropyrazine-2-carboxylate, 97% (CAS 330786-09-9)
- 3,6-Dichloropyrazine-2-carbaldehyde (CAS 1357172-39-4)
- 3,5-Dichloropyrazine-2-carbaldehyde (CAS 136866-27-8)
Recommended Standards
- 4,6-Dichloropyrimidine-2-carboxylic acid (CAS 684220-30-2)
- 5,6-Dichloropyrimidine-4-carboxylic acid (CAS 914916-97-5)
- 4,6-Dichloro-5-pyrimidinecarboxylic Acid (CAS 87600-98-4)
- 1-Bromo-3,4-difluorobenzene (CAS 348-61-8)
- Ethane-1,2-diyl dicarbamimidothioate dihydrobromide (CAS 6943-65-3)
- 2-Chloro-1-methyl-1H-imidazo[4,5-b]pyridine (CAS 65550-24-5)
- 1,1,4,4-Tetramethyl-6-nitro-1,2,3,4-tetrahydronaphthalene (CAS 102121-55-1)
- 2-[1-(2,4-dichlorophenyl)-5-oxo-4,5-dihydro-1H-pyrazol-3-yl]acetic acid (CAS 1094361-21-3)
- Tetrahydro-2H-pyranamine (CAS 64474-04-0)
- 8-Chloro-2-(2-methoxyphenyl)quinoline-4-carboxylic acid (CAS 862649-89-6)
- tert-Butyl ((5-chloro-4-oxo-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydrophthalazin-1-yl)methyl)carbamate (CAS 2836224-64-5)
- Decoyinine (CAS 2004-04-8)
- Ethyl 5-amino-1-(4-(chlorodifluoromethoxy)phenyl)-1H-pyrazole-4-carboxylate (CAS 400073-88-3)
- Antistasin-Related Peptide (CAS 161561-46-2)
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