1-Bromo-3,4-difluorobenzene CAS 348-61-8
| CAS No. | 348-61-8 |
| Molecular Formula | C6H3BrF2 |
| Molecular Weight | 192.99 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-Bromo-3,4-difluorobenzene.
1-Bromo-3,4-difluorobenzene (CAS 348-61-8) is a high-purity analytical reference standard with the molecular formula C6H3BrF2 and a molecular weight of 192.99 g/mol.
Structurally, 1-Bromo-3,4-difluorobenzene (C6H3BrF2) contains fluorine/bromine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 192.99 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H3BrF2 |
| Molecular Weight | 192.99 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 1-Bromo-2,3-difluorobenzene (CAS 38573-88-5)
- 1-Bromo-2,4-difluorobenzene (CAS 348-57-2)
- 2-Bromo-1,4-difluorobenzene (CAS 399-94-0)
- 1-Bromo-3,5-difluorobenzene (CAS 461-96-1)
- 3-Bromo-4,5-dihydroisoxazole-5-carboxylic acid amide (CAS 1030613-69-4)
- 5-Bromo-1-methylimidazolidine-2,4-dione (CAS 113259-78-2)
- 2-(5-Bromo-1,3,4-oxadiazol-2-yl)ethan-1-ol (CAS 1781571-30-9)
- 4-Bromo-5-methoxyfuran-2(5H)-one (CAS 62594-18-7)
Recommended Standards
- 5,6-Dichloropyrimidine-4-carboxylic acid (CAS 914916-97-5)
- 5,6-Dichloropyrazine-2-carboxylic acid (CAS 76537-42-3)
- 4,6-Dichloropyrimidine-2-carboxylic acid (CAS 684220-30-2)
- 4,6-Dichloro-5-pyrimidinecarboxylic Acid (CAS 87600-98-4)
- 8-Methyl-5-oxo-5H-thiazolo[3,2-a]pyridine-3-carboxylic acid (CAS 2387596-73-6)
- 1,3-Bis(2,6-di-i-propylphenyl)imidazolidin-2-ylidene)(2-i-propoxy-5-nitrobenzylidene) ruthenium(II) dichloride (CAS 928795-51-1)
- 4,6-Dichloro-N-isopropylpyrimidin-5-amine (CAS 1226804-11-0)
- 1-(3-Chlorophenyl)hexane-1,3-dione (CAS 1247176-35-7)
- Trans-3-fluoro-5,6-dihydroquinoline-5,6-diol (CAS 148324-56-5)
- (chloromethylene)bis(trimethylsilane) 5926-35-2 Bis(trimethylsilyl)methyl chloride (CAS 5926-35-2)
- 3-(2-Bromo-6-fluorophenyl)propanoic acid (CAS 1261775-91-0)
- 5-Bromo-N-(2-((3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl)methyl)phenyl)furan-2-carboxamide (CAS 1798018-62-8)
- 5-Chloro-2-iodo-3H-indole (CAS 1388032-50-7)
- Palmitoyl Tripeptide-1 TFA salt (CAS 2803375-47-3)
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