(R)-Methyl 2-amino-2-(3-nitrophenyl)acetate CAS 76604-97-2
| CAS No. | 76604-97-2 |
| Molecular Formula | C10H12N2O4 |
| Molecular Weight | 224.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies (R)-Methyl 2-amino-2-(3-nitrophenyl)acetate (CAS 76604-97-2), a certified reference material (molecular formula C10H12N2O4, MW 224.21 g/mol) for analytical method development and quality control.
The molecular framework of (R)-Methyl 2-amino-2-(3-nitrophenyl)acetate (C10H12N2O4) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H12N2O4 |
| Molecular Weight | 224.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Nitrogen Atoms | 2 |
Recommended Standards
- (R)-8-(2-Amino-1-hydroxyethyl)-6-hydroxy-2H-benzo[b][1,4]oxazin-3(4H)-one (CAS 2138872-60-1)
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- (S)-2-Amino-4-(4-nitrophenyl)butanoic acid (CAS 705919-70-6)
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- (2,5-Dimethyl-pyrrolidin-1-yl)-{2-hydroxy-6-[2-(4-hydroxy-phenyl)-ethyl]-phenyl}-methanone (CAS 1171924-53-0)
- SNPB (CAS 663598-85-4)
- 2-(Isopropylamino)-2-methyl-1-propanol (CAS 90434-44-9)
- Tert-butyl 4,4-difluoro-2,7-diazaspiro[4.5]Decane-7-carboxylate (CAS 1263181-67-4)
- Ethyl 3-(4-iodophenyl)-1H-1,2,4-triazole-5-carboxylate (CAS 1285291-39-5)
- Insulin Degludec Impurity 27 (CAS CATO-C4X-215727)
Why CATO?
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