4'-Fluoro-2-hydroxychalcone CAS 76626-08-9
| CAS No. | 76626-08-9 |
| Molecular Formula | C15H11FO2 |
| Molecular Weight | 242.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 242.25 g/mol gives 4'-Fluoro-2-hydroxychalcone distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4'-Fluoro-2-hydroxychalcone (CAS 76626-08-9), molecular formula C15H11FO2 and molecular weight 242.25 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4'-Fluoro-2-hydroxychalcone (C15H11FO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4'-Fluoro-2-hydroxychalcone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H11FO2 |
| Molecular Weight | 242.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | F-containing |
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Recommended Standards
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- N-Cyclopropylpteridin-4-amine (CAS 1774903-82-0)
- 1-(2-Nitrophenyl)azetidine (CAS 90557-58-7)
- DCG04 (CAS 314263-42-8)
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