2-Chloro-4-hydroxyphenylboronic acid CAS 766549-26-2
| CAS No. | 766549-26-2 |
| Molecular Formula | C6H6BClO3 |
| Molecular Weight | 172.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Chloro-4-hydroxyphenylboronic acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-Chloro-4-hydroxyphenylboronic acid (CAS 766549-26-2), molecular formula C6H6BClO3 and molecular weight 172.37 g/mol, is a CATO reference standard with documented purity and traceability.
2-Chloro-4-hydroxyphenylboronic acid (C6H6BClO3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H6BClO3 |
| Molecular Weight | 172.37 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
Related Chloro Standards
- (3-Chloro-5-hydroxyphenyl)boronic acid (CAS 1214900-52-3)
- (4-Chloro-2-hydroxyphenyl)boronic acid (CAS 1238196-66-1)
- (3-Chloro-4-hydroxyphenyl)boronic acid (CAS 182344-13-4)
- (2-Chloro-5-hydroxyphenyl)boronic acid (CAS 913835-71-9)
- (3-Chloro-2-hydroxyphenyl)boronic acid (CAS 951655-50-8)
- 2-Chloro-3-hydroxyphenylboronic Acid (CAS 854778-29-3)
- 2-Chloro-6-hydroxyphenylboronic Acid (CAS 958646-70-3)
- 4-Chloro-3-hydroxyphenylboronic Acid (CAS 915201-06-8)
Recommended Standards
- 5-Chloro-2-hydroxyphenylboronic Acid (CAS 89488-25-5)
- (2-Amino-5-chloropyridin-4-yl)boronic acid (CAS 1222522-34-0)
- (6-Amino-4-chloropyridin-3-yl)boronic acid (CAS 1225228-21-6)
- (6-Amino-2-chloropyridin-3-yl)boronic acid (CAS 1310404-77-3)
- N1,N2-Bis(4-methoxyphenyl)-1-methylhydrazine-1,2-bis(carbothioamide) (CAS 455880-00-9)
- tert-Butyl (3S,4S)-3-amino-4-fluoropiperidine-1-carboxylate (CAS 1290191-71-7)
- Dextrorphan-d3 Tartrate Salt (CAS 1426174-16-4)
- 2-((2-Carboxyphenyl)amino)-3-methoxybenzoic acid (CAS 88377-32-6)
- (3R,4R)-3-Isopropyl-1,4-dimethylpyrrolidine-2,5-dione (CAS 193819-92-0)
- 5,6-dihydropyrazolo[1,5-d][1,2,4]triazine-4,7-dione (CAS 56976-96-6)
- Tenofovir Disoproxil Impurity 101 (CAS CATO-C4X-1076101)
- tert-butyl 3-(5-(3-cyano-6-(3,6-dihydro-2H-pyran-4-yl)pyrazolo[1,5-a]pyridin-4-yl)pyrazin-2-yl)-3,6-diazabicyclo[3.1.1]heptane-6-carboxylate (CAS CATO-C3D-262142)
- 5-(M-tolyloxy)furan-2-carbaldehyde (CAS 1082167-88-1)
- Semaglutide impurity 267 (CAS CATO-C4X-2226267)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com