6-chloro-1H-indole-3-carboxylic acid CAS 76655-02-2
| CAS No. | 76655-02-2 |
| Molecular Formula | C9H6ClNO2 |
| Molecular Weight | 195.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 6-chloro-1H-indole-3-carboxylic acid (CAS 76655-02-2), a certified reference material (molecular formula C9H6ClNO2, MW 195.60 g/mol) for analytical method development and quality control.
6-chloro-1H-indole-3-carboxylic acid (C9H6ClNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 6-chloro-1H-indole-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H6ClNO2 |
| Molecular Weight | 195.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related chloro Standards
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- 7-Chloro-1H-indole-6-carboxylic acid (CAS 1055320-72-3)
- 5-Chloro-2-(oxazol-2-yl)phenol (CAS 1070796-25-6)
- 5-Chloro-6-methylindoline-2,3-dione (CAS 107583-35-7)
- 5-Chloro-2-(isoxazol-5-yl)phenol (CAS 107825-97-8)
- 5-Acetyl-2-chloro-4-hydroxybenzonitrile (CAS 115651-31-5)
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Recommended Standards
- 5-Chlorobenzofuran-2-carboxamide (CAS 35351-20-3)
- 6-Chloro-2-methyl-4H-benzo[d][1,3]oxazin-4-one (CAS 7033-50-3)
- 5-Chloro-4-methylindoline-2,3-dione (CAS 637347-66-1)
- 6-Chloro-2-oxoindoline-3-carbaldehyde (CAS 52508-91-5)
- 2-(5-Bromo-1,3-dioxoisoindolin-2-yl)benzoic acid (CAS 294194-23-3)
- 1-Pyridin-3-yl-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine (CAS 865546-36-7)
- 2-Amino-6-methoxy-4-methylphenol (CAS 862730-25-4)
- 2-Amino-3-bromoquinolin-7-ol (CAS 2086769-19-7)
- Dolutegravir Impurity 14 (CAS 127958-23-0)
- N-(5-Oxo-1-(2,2,2-trifluoroethyl)-4,5-dihydro-1H-pyrazol-3-yl)acrylamide (CAS 27204-98-4)
- 1-[(4-Fluorophenyl)methyl]-4-nitro-1h-pyrazole (CAS 898052-77-2)
- Flurbiprofen Impurity 26 (CAS 64858-90-8)
- 6-Methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-3-amine (CAS 148777-83-7)
- Semaglutide impurity 86 (CAS CATO-C4X-152686)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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