2,1,3-Benzothiadiazol-4-ol CAS 767-66-8
| CAS No. | 767-66-8 |
| Molecular Formula | C6H4N2OS |
| Molecular Weight | 152.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2,1,3-Benzothiadiazol-4-ol (C6H4N2OS) is characterized by an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
2,1,3-Benzothiadiazol-4-ol (CAS 767-66-8) is a high-purity analytical reference standard with the molecular formula C6H4N2OS and a molecular weight of 152.17 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H4N2OS |
| Molecular Weight | 152.17 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Benzothiadiazol Standards
- 1,2,3-benzothiadiazol-5-amine (CAS 1753-29-3)
- 3338-93-0 5-Methyl-2,1,3-benzothiadiazol-4-amine MFCD00185827 (CAS 3338-93-0)
- 2,1,3-Benzothiadiazol-5-ylisothiocyanate (CAS 337508-62-0)
- 2-(2,1,3-Benzothiadiazol-4-yl)acetic acid (CAS 42816-77-3)
- 2-(2,1,3-Benzothiadiazol-5-yl)acetic acid (CAS 55937-37-6)
- n-(2,1,3-Benzothiadiazol-4-yl)-2-chloroacetamide (CAS 175203-29-9)
- 3-(1,2,3-Benzothiadiazol-5-yl)-3-azabicyclo[3.1.0]hexane-2,4-dione (CAS 866156-78-7)
- N-(2,1,3-Benzothiadiazol-4-ylsulfonyl)glycine (CAS 312591-21-2)
Recommended Standards
- 2-(Thiophen-2-yl)-1,3,4-oxadiazole (CAS 35403-88-4)
- 2,4-Dimethyl-3-fluorobenzaldehyde (CAS 363134-36-5)
- 2-(Methylsulfonyl)propanoic acid (CAS 809280-27-1)
- 2,8-Dimethyl-imidazo[1,2-a]pyridine-3-carbaldehyde (CAS 820845-85-0)
- Amifostine Impurity 2 (CAS 58205-87-1)
- 4-Amino-5-(difluoromethyl)-3-fluoropyridin-2-ol (CAS 1806792-72-2)
- 4'-(Aminomethyl)-[1,1'-biphenyl]-4-carboxylic acid hydrochloride (CAS 578026-68-3)
- N-Boc-trans-4-azido-L-proline (CAS 132622-68-5)
- Erucic Acid (CAS 112-86-7)
- 5-Butyl-2,2-dimethyl-N-(2-morpholinoethyl)-1,4-dihydro-2H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-8-amine (CAS 372085-49-9)
- 6-Bromo-3-chloroisoquinoline (CAS 552331-06-3)
- 2-(2-(4-Fluorobenzamido)thiazol-4-yl)acetic acid (CAS 177957-48-1)
- 1-(cis-Hexahydropyrrolo[3,4-b]pyrrol-1(2H)-yl)propan-1-one (CAS 1218709-74-0)
- Semaglutide impurity 193 (CAS CATO-C4X-2226193)
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